Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruit
Zinc oxide nanoparticles (ZnO NPs) are one of the most widely used mineral particles. These nanoparticles are biocompatible and safe which can be used in medical-related industries. In this study, ZnO NPs were synthesized through an aqueous extract of Prosopis farcta fruit. Biosynthesized nanopartic...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-01-01
|
| Series: | Green Chemistry Letters and Reviews |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/17518253.2020.1717005 |
| _version_ | 1818527721217589248 |
|---|---|
| author | Abdolhossien Miri Mehrdad Khatami Omolbanin Ebrahimy Mina Sarani |
| author_facet | Abdolhossien Miri Mehrdad Khatami Omolbanin Ebrahimy Mina Sarani |
| author_sort | Abdolhossien Miri |
| collection | DOAJ |
| description | Zinc oxide nanoparticles (ZnO NPs) are one of the most widely used mineral particles. These nanoparticles are biocompatible and safe which can be used in medical-related industries. In this study, ZnO NPs were synthesized through an aqueous extract of Prosopis farcta fruit. Biosynthesized nanoparticles were identified through Ultraviolet–visible (UV–Vis), Powder X-Ray Diffraction (PXRD), Field Emission Scanning Electron Microscopy (FESEM), Energy Dispersive X-ray analysis (EDX), and Transmission Electron Microscopy (TEM) methods. The results of electron imaging showed that biosynthesized nanoparticles are hexagonal in shape with range size between 40 and 50 nm. Electron spectroscopy results showed that the bandgap of biosynthesized nanoparticles is 3.9 eV. The results of antifungal assay against Candida albicans showed 32–64 and 128–512 µg/ml values for minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC), respectively. Cytotoxicity of nanoparticles against breast cancer cells (MCF7) was performed using WST-1 assay and its IC50 was obtained 500 μg/ml. |
| first_indexed | 2024-12-11T06:39:58Z |
| format | Article |
| id | doaj.art-ccc11b7cbc214e2e8bdcbee83da83b13 |
| institution | Directory Open Access Journal |
| issn | 1751-8253 1751-7192 |
| language | English |
| last_indexed | 2024-12-11T06:39:58Z |
| publishDate | 2020-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Green Chemistry Letters and Reviews |
| spelling | doaj.art-ccc11b7cbc214e2e8bdcbee83da83b132022-12-22T01:17:16ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922020-01-01131273310.1080/17518253.2020.17170051717005Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruitAbdolhossien Miri0Mehrdad Khatami1Omolbanin Ebrahimy2Mina Sarani3Zabol University of Medical SciencesBam University of Medical SciencesUniversity of ZabolBam University of Medical SciencesZinc oxide nanoparticles (ZnO NPs) are one of the most widely used mineral particles. These nanoparticles are biocompatible and safe which can be used in medical-related industries. In this study, ZnO NPs were synthesized through an aqueous extract of Prosopis farcta fruit. Biosynthesized nanoparticles were identified through Ultraviolet–visible (UV–Vis), Powder X-Ray Diffraction (PXRD), Field Emission Scanning Electron Microscopy (FESEM), Energy Dispersive X-ray analysis (EDX), and Transmission Electron Microscopy (TEM) methods. The results of electron imaging showed that biosynthesized nanoparticles are hexagonal in shape with range size between 40 and 50 nm. Electron spectroscopy results showed that the bandgap of biosynthesized nanoparticles is 3.9 eV. The results of antifungal assay against Candida albicans showed 32–64 and 128–512 µg/ml values for minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC), respectively. Cytotoxicity of nanoparticles against breast cancer cells (MCF7) was performed using WST-1 assay and its IC50 was obtained 500 μg/ml.http://dx.doi.org/10.1080/17518253.2020.1717005zinc oxide nanoparticlesprosopis farcta fruitmfcwst-1 |
| spellingShingle | Abdolhossien Miri Mehrdad Khatami Omolbanin Ebrahimy Mina Sarani Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruit Green Chemistry Letters and Reviews zinc oxide nanoparticles prosopis farcta fruit mfc wst-1 |
| title | Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruit |
| title_full | Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruit |
| title_fullStr | Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruit |
| title_full_unstemmed | Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruit |
| title_short | Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruit |
| title_sort | cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of prosopis farcta fruit |
| topic | zinc oxide nanoparticles prosopis farcta fruit mfc wst-1 |
| url | http://dx.doi.org/10.1080/17518253.2020.1717005 |
| work_keys_str_mv | AT abdolhossienmiri cytotoxicandantifungalstudiesofbiosynthesizedzincoxidenanoparticlesusingextractofprosopisfarctafruit AT mehrdadkhatami cytotoxicandantifungalstudiesofbiosynthesizedzincoxidenanoparticlesusingextractofprosopisfarctafruit AT omolbaninebrahimy cytotoxicandantifungalstudiesofbiosynthesizedzincoxidenanoparticlesusingextractofprosopisfarctafruit AT minasarani cytotoxicandantifungalstudiesofbiosynthesizedzincoxidenanoparticlesusingextractofprosopisfarctafruit |