Osseointegration of zirconia implants compared with titanium: an <it>in vivo </it>study

<p>Abstract</p> <p>Background</p> <p>Titanium and titanium alloys are widely used for fabrication of dental implants. Since the material composition and the surface topography of a biomaterial play a fundamental role in osseointegration, various chemical and physical su...

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Main Authors: Lauer Hans-Christoph, Kiattavorncharoen Sirichai, Wiesmann Hans-Peter, Naujoks Christian, Ommerborn Michelle, Zipprich Holger, Depprich Rita, Meyer Ulrich, Kübler Norbert R, Handschel Jörg
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Head & Face Medicine
Online Access:http://www.head-face-med.com/content/4/1/30
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author Lauer Hans-Christoph
Kiattavorncharoen Sirichai
Wiesmann Hans-Peter
Naujoks Christian
Ommerborn Michelle
Zipprich Holger
Depprich Rita
Meyer Ulrich
Kübler Norbert R
Handschel Jörg
author_facet Lauer Hans-Christoph
Kiattavorncharoen Sirichai
Wiesmann Hans-Peter
Naujoks Christian
Ommerborn Michelle
Zipprich Holger
Depprich Rita
Meyer Ulrich
Kübler Norbert R
Handschel Jörg
author_sort Lauer Hans-Christoph
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Titanium and titanium alloys are widely used for fabrication of dental implants. Since the material composition and the surface topography of a biomaterial play a fundamental role in osseointegration, various chemical and physical surface modifications have been developed to improve osseous healing. Zirconia-based implants were introduced into dental implantology as an altenative to titanium implants. Zirconia seems to be a suitable implant material because of its tooth-like colour, its mechanical properties and its biocompatibility. As the osseointegration of zirconia implants has not been extensively investigated, the aim of this study was to compare the osseous healing of zirconia implants with titanium implants which have a roughened surface but otherwise similar implant geometries.</p> <p>Methods</p> <p>Forty-eight zirconia and titanium implants were introduced into the tibia of 12 minipigs. After 1, 4 or 12 weeks, animals were sacrificed and specimens containing the implants were examined in terms of histological and ultrastructural techniques.</p> <p>Results</p> <p>Histological results showed direct bone contact on the zirconia and titanium surfaces. Bone implant contact as measured by histomorphometry was slightly better on titanium than on zirconia surfaces. However, a statistically significant difference between the two groups was not observed.</p> <p>Conclusion</p> <p>The results demonstrated that zirconia implants with modified surfaces result in an osseointegration which is comparable with that of titanium implants.</p>
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spelling doaj.art-ccc49726563b49d5b856489fad9e41092022-12-21T23:12:50ZengBMCHead & Face Medicine1746-160X2008-12-01413010.1186/1746-160X-4-30Osseointegration of zirconia implants compared with titanium: an <it>in vivo </it>studyLauer Hans-ChristophKiattavorncharoen SirichaiWiesmann Hans-PeterNaujoks ChristianOmmerborn MichelleZipprich HolgerDepprich RitaMeyer UlrichKübler Norbert RHandschel Jörg<p>Abstract</p> <p>Background</p> <p>Titanium and titanium alloys are widely used for fabrication of dental implants. Since the material composition and the surface topography of a biomaterial play a fundamental role in osseointegration, various chemical and physical surface modifications have been developed to improve osseous healing. Zirconia-based implants were introduced into dental implantology as an altenative to titanium implants. Zirconia seems to be a suitable implant material because of its tooth-like colour, its mechanical properties and its biocompatibility. As the osseointegration of zirconia implants has not been extensively investigated, the aim of this study was to compare the osseous healing of zirconia implants with titanium implants which have a roughened surface but otherwise similar implant geometries.</p> <p>Methods</p> <p>Forty-eight zirconia and titanium implants were introduced into the tibia of 12 minipigs. After 1, 4 or 12 weeks, animals were sacrificed and specimens containing the implants were examined in terms of histological and ultrastructural techniques.</p> <p>Results</p> <p>Histological results showed direct bone contact on the zirconia and titanium surfaces. Bone implant contact as measured by histomorphometry was slightly better on titanium than on zirconia surfaces. However, a statistically significant difference between the two groups was not observed.</p> <p>Conclusion</p> <p>The results demonstrated that zirconia implants with modified surfaces result in an osseointegration which is comparable with that of titanium implants.</p>http://www.head-face-med.com/content/4/1/30
spellingShingle Lauer Hans-Christoph
Kiattavorncharoen Sirichai
Wiesmann Hans-Peter
Naujoks Christian
Ommerborn Michelle
Zipprich Holger
Depprich Rita
Meyer Ulrich
Kübler Norbert R
Handschel Jörg
Osseointegration of zirconia implants compared with titanium: an <it>in vivo </it>study
Head & Face Medicine
title Osseointegration of zirconia implants compared with titanium: an <it>in vivo </it>study
title_full Osseointegration of zirconia implants compared with titanium: an <it>in vivo </it>study
title_fullStr Osseointegration of zirconia implants compared with titanium: an <it>in vivo </it>study
title_full_unstemmed Osseointegration of zirconia implants compared with titanium: an <it>in vivo </it>study
title_short Osseointegration of zirconia implants compared with titanium: an <it>in vivo </it>study
title_sort osseointegration of zirconia implants compared with titanium an it in vivo it study
url http://www.head-face-med.com/content/4/1/30
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