Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro

Background and Aims: Dental caries is one of the most common infectious diseases which could be prevented in various ways. The aim of the present study was to evaluate the effect of a toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient caries.  ...

Full description

Bibliographic Details
Main Authors: Haghgoo Roza, Rezvani Mohammad Bagher, Haghgoo Hamid Reaza, Ameli Nazila, Zeinabadi Mehdi Salehi
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2015-01-01
Series:Journal of Dental Medicine
Subjects:
Online Access:http://jdm.tums.ac.ir/browse.php?a_code=A-10-25-766&slc_lang=en&sid=1
_version_ 1818937205753643008
author Haghgoo Roza
Rezvani Mohammad Bagher
Haghgoo Hamid Reaza
Ameli Nazila
Zeinabadi Mehdi Salehi
author_facet Haghgoo Roza
Rezvani Mohammad Bagher
Haghgoo Hamid Reaza
Ameli Nazila
Zeinabadi Mehdi Salehi
author_sort Haghgoo Roza
collection DOAJ
description Background and Aims: Dental caries is one of the most common infectious diseases which could be prevented in various ways. The aim of the present study was to evaluate the effect of a toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient caries.   Materials and Methods: 9 sound first premolar teeth of maxilla and mandible were sectioned to four pieces. 6 specimens were stored in distilled water as control group. The remaining 30 specimens were demineralized for 72 hours and then their microhardness was measured. 0, 0.5, 1, 2 and 5% wt nano-hydroxyapatite were added to the solution of distilled water and toothpaste. Specimens were divided into 5 groups (N=6) and after demineralization, each group were randomly immersed in the above-mentioned solutions for 15 minutes. Next, specimens were kept in artificial saliva for 1 hour followed by immersion in the related remineralizing solution for another 15 minutes. This procedure was repeated for 5 days. Finally, the microhardness of the teeth was measured. Data were analyzed using repeated measures analysis of variance (ANOVA).   Results: The microhardness of demineralized teeth was increased following exposure to different concentrations of nano-hydroxyapatite, but this increase was not statistically significant (P=0.62).   Conclusion: Nano-hydroxy apatite can enhance remineralization and increase the tooth microhardness although this increase was not significant.
first_indexed 2024-12-20T05:48:16Z
format Article
id doaj.art-ccc6685616fb42aa90dec1e19944f234
institution Directory Open Access Journal
issn 1024-641X
2008-2444
language fas
last_indexed 2024-12-20T05:48:16Z
publishDate 2015-01-01
publisher Tehran University of Medical Sciences
record_format Article
series Journal of Dental Medicine
spelling doaj.art-ccc6685616fb42aa90dec1e19944f2342022-12-21T19:51:15ZfasTehran University of Medical SciencesJournal of Dental Medicine1024-641X2008-24442015-01-01274254258Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitroHaghgoo Roza 0Rezvani Mohammad Bagher 1Haghgoo Hamid Reaza 2Ameli Nazila 3Zeinabadi Mehdi Salehi 4 Background and Aims: Dental caries is one of the most common infectious diseases which could be prevented in various ways. The aim of the present study was to evaluate the effect of a toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient caries.   Materials and Methods: 9 sound first premolar teeth of maxilla and mandible were sectioned to four pieces. 6 specimens were stored in distilled water as control group. The remaining 30 specimens were demineralized for 72 hours and then their microhardness was measured. 0, 0.5, 1, 2 and 5% wt nano-hydroxyapatite were added to the solution of distilled water and toothpaste. Specimens were divided into 5 groups (N=6) and after demineralization, each group were randomly immersed in the above-mentioned solutions for 15 minutes. Next, specimens were kept in artificial saliva for 1 hour followed by immersion in the related remineralizing solution for another 15 minutes. This procedure was repeated for 5 days. Finally, the microhardness of the teeth was measured. Data were analyzed using repeated measures analysis of variance (ANOVA).   Results: The microhardness of demineralized teeth was increased following exposure to different concentrations of nano-hydroxyapatite, but this increase was not statistically significant (P=0.62).   Conclusion: Nano-hydroxy apatite can enhance remineralization and increase the tooth microhardness although this increase was not significant.http://jdm.tums.ac.ir/browse.php?a_code=A-10-25-766&slc_lang=en&sid=1Carious lesions Nano-hydroxyapatite Remineralization
spellingShingle Haghgoo Roza
Rezvani Mohammad Bagher
Haghgoo Hamid Reaza
Ameli Nazila
Zeinabadi Mehdi Salehi
Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro
Journal of Dental Medicine
Carious lesions
Nano-hydroxyapatite
Remineralization
title Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro
title_full Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro
title_fullStr Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro
title_full_unstemmed Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro
title_short Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro
title_sort evaluation of iranian toothpaste containing different concentrations of nano hydroxyapatite on the remineralization of incipient carious lesions in vitro
topic Carious lesions
Nano-hydroxyapatite
Remineralization
url http://jdm.tums.ac.ir/browse.php?a_code=A-10-25-766&slc_lang=en&sid=1
work_keys_str_mv AT haghgooroza evaluationofiraniantoothpastecontainingdifferentconcentrationsofnanohydroxyapatiteontheremineralizationofincipientcariouslesionsinvitro
AT rezvanimohammadbagher evaluationofiraniantoothpastecontainingdifferentconcentrationsofnanohydroxyapatiteontheremineralizationofincipientcariouslesionsinvitro
AT haghgoohamidreaza evaluationofiraniantoothpastecontainingdifferentconcentrationsofnanohydroxyapatiteontheremineralizationofincipientcariouslesionsinvitro
AT amelinazila evaluationofiraniantoothpastecontainingdifferentconcentrationsofnanohydroxyapatiteontheremineralizationofincipientcariouslesionsinvitro
AT zeinabadimehdisalehi evaluationofiraniantoothpastecontainingdifferentconcentrationsofnanohydroxyapatiteontheremineralizationofincipientcariouslesionsinvitro