Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review
Contrast agents is used in magnetic resonance imaging (MRI) to improve the visibility of the details of the organ structures. Gadolinium-based contrast agent (GBCA) has been used since 1988 in MRI for diagnostic and follow-up of patients, the gadolinium good properties make it an effective choice fo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | European Journal of Radiology Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352047723000291 |
| _version_ | 1797399100087336960 |
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| author | Nebal Iyad Muntaser S.Ahmad Sanaa G. Alkhatib Mohammad Hjouj |
| author_facet | Nebal Iyad Muntaser S.Ahmad Sanaa G. Alkhatib Mohammad Hjouj |
| author_sort | Nebal Iyad |
| collection | DOAJ |
| description | Contrast agents is used in magnetic resonance imaging (MRI) to improve the visibility of the details of the organ structures. Gadolinium-based contrast agent (GBCA) has been used since 1988 in MRI for diagnostic and follow-up of patients, the gadolinium good properties make it an effective choice for enhance the signal in MRI by increase its intensity and shortening the relaxation time of the proton. Recently, many studies show a gadolinium deposition in different human organs due to release of free gadolinium various body organs or tissue, which led to increased concern about the use of gadolinium agents, in this study, the potential diseases that may affect the patient and side effects that appear on the patient and related to accumulation of gadolinium were clarified, the study focused on the organs such as brain and bones in which gadolinium deposition was found and the lesions associated with it, and the diseases associated with gadolinium retention includes Nephrogenic Systemic Fibrosis (NSF) and Gadolinium deposition disease (GDD). Some studies tended to improve the contrast agents by developing a new non-gadolinium agents or development of next-generation gadolinium agents. In this review article the latest knowledge about MRI contrast agent. |
| first_indexed | 2024-03-09T01:34:35Z |
| format | Article |
| id | doaj.art-ccc769744ea54269bff639eadde76178 |
| institution | Directory Open Access Journal |
| issn | 2352-0477 |
| language | English |
| last_indexed | 2024-03-09T01:34:35Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | European Journal of Radiology Open |
| spelling | doaj.art-ccc769744ea54269bff639eadde761782023-12-09T06:06:36ZengElsevierEuropean Journal of Radiology Open2352-04772023-12-0111100503Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature reviewNebal Iyad0Muntaser S.Ahmad1Sanaa G. Alkhatib2Mohammad Hjouj3Ibn Rushd Radiology Centre, Hebron, PalestineIbn Rushd Radiology Centre, Hebron, Palestine; Department of Medical Imaging, Faculty of Allied Medical Health, Palestine Ahliya University, Dheisha, Bethlehem, Palestine; Corresponding author at: Department of Medical Imaging, Faculty of Allied Medical Health, Palestine Ahliya University, Dheisha, Bethlehem, Palestine.Department of Medical Imaging, Faculty of Allied Medical Health, Palestine Ahliya University, Dheisha, Bethlehem, PalestineMedical Imaging Department, Faculty of Health Professions, Al-Quds University, Abu Deis - Main Campus, Jerusalem, Palestine; Corresponding author.Contrast agents is used in magnetic resonance imaging (MRI) to improve the visibility of the details of the organ structures. Gadolinium-based contrast agent (GBCA) has been used since 1988 in MRI for diagnostic and follow-up of patients, the gadolinium good properties make it an effective choice for enhance the signal in MRI by increase its intensity and shortening the relaxation time of the proton. Recently, many studies show a gadolinium deposition in different human organs due to release of free gadolinium various body organs or tissue, which led to increased concern about the use of gadolinium agents, in this study, the potential diseases that may affect the patient and side effects that appear on the patient and related to accumulation of gadolinium were clarified, the study focused on the organs such as brain and bones in which gadolinium deposition was found and the lesions associated with it, and the diseases associated with gadolinium retention includes Nephrogenic Systemic Fibrosis (NSF) and Gadolinium deposition disease (GDD). Some studies tended to improve the contrast agents by developing a new non-gadolinium agents or development of next-generation gadolinium agents. In this review article the latest knowledge about MRI contrast agent.http://www.sciencedirect.com/science/article/pii/S2352047723000291MRIContrast medicaGBCAGDDNSF |
| spellingShingle | Nebal Iyad Muntaser S.Ahmad Sanaa G. Alkhatib Mohammad Hjouj Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review European Journal of Radiology Open MRI Contrast medica GBCA GDD NSF |
| title | Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review |
| title_full | Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review |
| title_fullStr | Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review |
| title_full_unstemmed | Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review |
| title_short | Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review |
| title_sort | gadolinium contrast agents challenges and opportunities of a multidisciplinary approach literature review |
| topic | MRI Contrast medica GBCA GDD NSF |
| url | http://www.sciencedirect.com/science/article/pii/S2352047723000291 |
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