Characterization of Dermal Fibroblasts as a Cell Source for Pediatric Tissue Engineered Heart Valves

Characterization of Dermal Fibroblasts as a Cell Source for Pediatric Tissue Engineered Heart Valves

There is continued debate regarding the appropriate cell type to replace valvular interstitial cells (VICs) in tissue engineered heart valves (TEHVs), particularly for pediatric patients. In this work, neonatal human dermal fibroblasts (nhDFFs) were compared to human pediatric VICs (hpVICs), based o...

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Bibliographic Details
Main Authors: Monica M. Fahrenholtz, Huiwen Liu, Debra L. Kearney, Lalita Wadhwa, Charles D. Fraser, K. Jane Grande-Allen
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
fibroblasts
pediatric
valvular interstitial cell
VIC
TEHV
extracellular matrix
substrate
Online Access:http://www.mdpi.com/2308-3425/1/2/146

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