Subsequent Pregnancy after Preterm Prelabor Rupture of Membranes before 27 Weeks' Gestation
Abstract Objective Midtrimester preterm prelabor rupture of membranes (PPROM) has a high rate of neonatal mortality and morbidity. The aim of this study was to study outcomes of subsequent pregnancies after a pregnancy with PPROM before 27 weeks' gestation. Study Desig...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2013-08-01
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| Series: | American Journal of Perinatology Reports |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0033-1353389 |
| _version_ | 1811323301955371008 |
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| author | Jantien L. van der Heyden Sander M. J. van Kuijk David P. van der Ham Kim J. B. Notten Timothy Janssen Jan G. Nijhuis Christine Willekes Martina Porath Joris A. van der Post Feico Halbertsma Eva Pajkrt Ben Willem J. Mol |
| author_facet | Jantien L. van der Heyden Sander M. J. van Kuijk David P. van der Ham Kim J. B. Notten Timothy Janssen Jan G. Nijhuis Christine Willekes Martina Porath Joris A. van der Post Feico Halbertsma Eva Pajkrt Ben Willem J. Mol |
| author_sort | Jantien L. van der Heyden |
| collection | DOAJ |
| description | Abstract
Objective Midtrimester preterm prelabor rupture of membranes (PPROM) has a high rate of neonatal mortality and morbidity. The aim of this study was to study outcomes of subsequent pregnancies after a pregnancy with PPROM before 27 weeks' gestation.
Study Design Retrospective study of subsequent pregnancies of women who suffered PPROM before 27 weeks' gestation from 1994 to 2009. The main outcome measure was the risk of recurrence of PPROM before 27 weeks' gestation. The authors also studied preterm birth and pregnancy outcome in the subsequent pregnancy. Finally, they assessed associative factors for subsequent premature delivery.
Results They identified 307 patients, of whom 118 women had a subsequent pregnancy. Of 99 women with complete outcome data, 9 women (9%) had PPROM before 27 weeks' gestation in a subsequent pregnancy and 35 women (35%) had a preterm delivery. In 58 (59%) of pregnancies no major complications occurred. They found three associative factors for premature delivery in a subsequent pregnancy: negative vaginal culture for Group B streptococcus, increasing maternal age and early gestational age at PPROM in the index pregnancy.
Conclusions Women with PPROM before 27 weeks have a 9% recurrence risk of early PPROM and a risk of 35% of having a preterm delivery in a subsequent pregnancy. |
| first_indexed | 2024-04-13T13:52:31Z |
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| issn | 2157-6998 2157-7005 |
| language | English |
| last_indexed | 2024-04-13T13:52:31Z |
| publishDate | 2013-08-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | American Journal of Perinatology Reports |
| spelling | doaj.art-ccd655895d5d4f5c9c37f4a13d6094b12022-12-22T02:44:18ZengThieme Medical Publishers, Inc.American Journal of Perinatology Reports2157-69982157-70052013-08-01030211311810.1055/s-0033-1353389Subsequent Pregnancy after Preterm Prelabor Rupture of Membranes before 27 Weeks' GestationJantien L. van der Heyden0Sander M. J. van Kuijk1David P. van der Ham2Kim J. B. Notten3Timothy Janssen4Jan G. Nijhuis5Christine Willekes6Martina Porath7Joris A. van der Post8Feico Halbertsma9Eva Pajkrt10Ben Willem J. Mol11Department of Obstetrics and Gynecology, Maastricht University Medical Center, GROW School for Oncology and Developmental Biology, The NetherlandsDepartment of Obstetrics and Gynecology, Maastricht University Medical Center, GROW School for Oncology and Developmental Biology, The NetherlandsDepartment of Obstetrics and Gynecology, Martini Hospital, Groningen, The NetherlandsDepartment of Obstetrics and Gynecology, VieCuri Medical Center, Venlo, The NetherlandsDepartment of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The NetherlandsDepartment of Obstetrics and Gynecology, Maastricht University Medical Center, GROW School for Oncology and Developmental Biology, The NetherlandsDepartment of Obstetrics and Gynecology, Maastricht University Medical Center, GROW School for Oncology and Developmental Biology, The NetherlandsDepartment of Obstetrics and Gynecology, Máxima Medical Center Veldhoven, The NetherlandsDepartment of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The NetherlandsDepartment of Neonatology, Máxima Medical Center Veldhoven, The NetherlandsDepartment of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The NetherlandsDepartment of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The NetherlandsAbstract Objective Midtrimester preterm prelabor rupture of membranes (PPROM) has a high rate of neonatal mortality and morbidity. The aim of this study was to study outcomes of subsequent pregnancies after a pregnancy with PPROM before 27 weeks' gestation. Study Design Retrospective study of subsequent pregnancies of women who suffered PPROM before 27 weeks' gestation from 1994 to 2009. The main outcome measure was the risk of recurrence of PPROM before 27 weeks' gestation. The authors also studied preterm birth and pregnancy outcome in the subsequent pregnancy. Finally, they assessed associative factors for subsequent premature delivery. Results They identified 307 patients, of whom 118 women had a subsequent pregnancy. Of 99 women with complete outcome data, 9 women (9%) had PPROM before 27 weeks' gestation in a subsequent pregnancy and 35 women (35%) had a preterm delivery. In 58 (59%) of pregnancies no major complications occurred. They found three associative factors for premature delivery in a subsequent pregnancy: negative vaginal culture for Group B streptococcus, increasing maternal age and early gestational age at PPROM in the index pregnancy. Conclusions Women with PPROM before 27 weeks have a 9% recurrence risk of early PPROM and a risk of 35% of having a preterm delivery in a subsequent pregnancy.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0033-1353389preterm rupture of membranesrecurrencepreterm birth |
| spellingShingle | Jantien L. van der Heyden Sander M. J. van Kuijk David P. van der Ham Kim J. B. Notten Timothy Janssen Jan G. Nijhuis Christine Willekes Martina Porath Joris A. van der Post Feico Halbertsma Eva Pajkrt Ben Willem J. Mol Subsequent Pregnancy after Preterm Prelabor Rupture of Membranes before 27 Weeks' Gestation American Journal of Perinatology Reports preterm rupture of membranes recurrence preterm birth |
| title | Subsequent Pregnancy after Preterm Prelabor Rupture of Membranes before 27 Weeks' Gestation |
| title_full | Subsequent Pregnancy after Preterm Prelabor Rupture of Membranes before 27 Weeks' Gestation |
| title_fullStr | Subsequent Pregnancy after Preterm Prelabor Rupture of Membranes before 27 Weeks' Gestation |
| title_full_unstemmed | Subsequent Pregnancy after Preterm Prelabor Rupture of Membranes before 27 Weeks' Gestation |
| title_short | Subsequent Pregnancy after Preterm Prelabor Rupture of Membranes before 27 Weeks' Gestation |
| title_sort | subsequent pregnancy after preterm prelabor rupture of membranes before 27 weeks gestation |
| topic | preterm rupture of membranes recurrence preterm birth |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0033-1353389 |
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