Assessing the association between smoking and hypertension: Smoking status, type of tobacco products, and interaction with alcohol consumption
BackgroundThe association between tobacco use and hypertension risk has been extensively researched but remains controversial, and few existing studies have considered the role of tobacco type and dosage response in this association. In this context, this study aims to provide epidemiological eviden...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1027988/full |
| _version_ | 1811168366907359232 |
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| author | Ningxin Gao Tao Liu Yawen Wang Min Chen Lisha Yu Chaowei Fu Kelin Xu |
| author_facet | Ningxin Gao Tao Liu Yawen Wang Min Chen Lisha Yu Chaowei Fu Kelin Xu |
| author_sort | Ningxin Gao |
| collection | DOAJ |
| description | BackgroundThe association between tobacco use and hypertension risk has been extensively researched but remains controversial, and few existing studies have considered the role of tobacco type and dosage response in this association. In this context, this study aims to provide epidemiological evidence for the possible relationship between tobacco smoking and future hypertension risk, with the tobacco type and consumption dose into consideration.MethodsThis study was based on 10-year follow-up data from the Guizhou Population Health Cohort conducted in southwest China. Multivariate Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals [95% confidence intervals (CIs)], and restricted cubic spline analyses were performed to visualize the dose-response association.ResultsA total of 5,625 participants (2,563 males and 3,062 females) were included in the final analysis. Heavy smokers of machine-rolled cigarettes had an elevated hypertension risk compared with non-smokers (HR: 1.50, 95% CI: 1.05–2.16). The interaction effects of heavy smoking-heavy drinking patterns increased the future hypertension risk, with an adjusted HR of 2.58 (95% CI: 1.06–6.33).ConclusionThis study did not find a significant association between overall tobacco use status and the risk of hypertension. However, heavy machine-rolled cigarette smokers had a statistically significant increased risk of hypertension compared with non-smokers, and a J-shape association has been found between the average daily consumption of machine-rolled cigarettes and the risk of hypertension. Besides, tobacco and alcohol consumption jointly increased the long-term hypertension risk. |
| first_indexed | 2024-04-10T16:25:07Z |
| format | Article |
| id | doaj.art-ccd7ed6312ab4629995e7c027a9c1bec |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-10T16:25:07Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-ccd7ed6312ab4629995e7c027a9c1bec2023-02-09T07:56:04ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-02-011010.3389/fcvm.2023.10279881027988Assessing the association between smoking and hypertension: Smoking status, type of tobacco products, and interaction with alcohol consumptionNingxin Gao0Tao Liu1Yawen Wang2Min Chen3Lisha Yu4Chaowei Fu5Kelin Xu6Ministry of Education Key Laboratory of Public Health Safety, Department of Biostatistics, School of Public Health, Fudan University, Shanghai, ChinaGuizhou Province Center for Disease Control and Prevention, Guiyang, Guizhou, ChinaMinistry of Education Key Laboratory of Public Health Safety, Department of Biostatistics, School of Public Health, Fudan University, Shanghai, ChinaGuizhou Province Center for Disease Control and Prevention, Guiyang, Guizhou, ChinaGuizhou Province Center for Disease Control and Prevention, Guiyang, Guizhou, ChinaMinistry of Education Key Laboratory of Public Health Safety, Department of Epidemiology, School of Public Health, Fudan University, Shanghai, ChinaMinistry of Education Key Laboratory of Public Health Safety, Department of Biostatistics, School of Public Health, Fudan University, Shanghai, ChinaBackgroundThe association between tobacco use and hypertension risk has been extensively researched but remains controversial, and few existing studies have considered the role of tobacco type and dosage response in this association. In this context, this study aims to provide epidemiological evidence for the possible relationship between tobacco smoking and future hypertension risk, with the tobacco type and consumption dose into consideration.MethodsThis study was based on 10-year follow-up data from the Guizhou Population Health Cohort conducted in southwest China. Multivariate Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals [95% confidence intervals (CIs)], and restricted cubic spline analyses were performed to visualize the dose-response association.ResultsA total of 5,625 participants (2,563 males and 3,062 females) were included in the final analysis. Heavy smokers of machine-rolled cigarettes had an elevated hypertension risk compared with non-smokers (HR: 1.50, 95% CI: 1.05–2.16). The interaction effects of heavy smoking-heavy drinking patterns increased the future hypertension risk, with an adjusted HR of 2.58 (95% CI: 1.06–6.33).ConclusionThis study did not find a significant association between overall tobacco use status and the risk of hypertension. However, heavy machine-rolled cigarette smokers had a statistically significant increased risk of hypertension compared with non-smokers, and a J-shape association has been found between the average daily consumption of machine-rolled cigarettes and the risk of hypertension. Besides, tobacco and alcohol consumption jointly increased the long-term hypertension risk.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1027988/fulltobacco usehypertensiondose-response associationcohort studyinteraction effect |
| spellingShingle | Ningxin Gao Tao Liu Yawen Wang Min Chen Lisha Yu Chaowei Fu Kelin Xu Assessing the association between smoking and hypertension: Smoking status, type of tobacco products, and interaction with alcohol consumption Frontiers in Cardiovascular Medicine tobacco use hypertension dose-response association cohort study interaction effect |
| title | Assessing the association between smoking and hypertension: Smoking status, type of tobacco products, and interaction with alcohol consumption |
| title_full | Assessing the association between smoking and hypertension: Smoking status, type of tobacco products, and interaction with alcohol consumption |
| title_fullStr | Assessing the association between smoking and hypertension: Smoking status, type of tobacco products, and interaction with alcohol consumption |
| title_full_unstemmed | Assessing the association between smoking and hypertension: Smoking status, type of tobacco products, and interaction with alcohol consumption |
| title_short | Assessing the association between smoking and hypertension: Smoking status, type of tobacco products, and interaction with alcohol consumption |
| title_sort | assessing the association between smoking and hypertension smoking status type of tobacco products and interaction with alcohol consumption |
| topic | tobacco use hypertension dose-response association cohort study interaction effect |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1027988/full |
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