ATACAmp: a tool for detecting ecDNA/HSRs from bulk and single-cell ATAC-seq data

ATACAmp: a tool for detecting ecDNA/HSRs from bulk and single-cell ATAC-seq data

Abstract Background High oncogene expression in cancer cells is a major cause of rapid tumor progression and drug resistance. Recent cancer genome research has shown that oncogenes as well as regulatory elements can be amplified in the form of extrachromosomal DNA (ecDNA) or subsequently integrated...

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Bibliographic Details
Main Authors: Hansen Cheng, Wenhao Ma, Kun Wang, Han Chu, Guangchao Bao, Yu Liao, Yawen Yuan, Yixiong Gou, Liting Dong, Jian Yang, Haoyang Cai
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Genomics
Subjects:
ecDNA
ATAC-seq
Cancer genome
Intratumor heterogeneity
Online Access:https://doi.org/10.1186/s12864-023-09792-6

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