The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016
Abstract Objectives Using the findings of the Global Burden of Disease Study (GBD), we report the burden of primary headache disorders in the Eastern Mediterranean Region (EMR) from 1990 to 2016. Methods We modelled headache disorders using DisMod-MR 2.1 Bayesian meta-regression tool to ensure consi...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-04-01
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| Series: | The Journal of Headache and Pain |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s10194-019-0990-3 |
| _version_ | 1828836011186061312 |
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| author | Kia Vosoughi Lars Jacob Stovner Timothy J. Steiner Maziar Moradi-Lakeh Seyed-Mohammad Fereshtehnejad Farshad Farzadfar Pouria Heydarpour Reza Malekzadeh Mohsen Naghavi Mohammad Ali Sahraian Sadaf G. Sepanlou Arash Tehrani-Banihashemi Reza Majdzadeh Valery L. Feigin Theo Vos Ali H. Mokdad Christopher J. L. Murray |
| author_facet | Kia Vosoughi Lars Jacob Stovner Timothy J. Steiner Maziar Moradi-Lakeh Seyed-Mohammad Fereshtehnejad Farshad Farzadfar Pouria Heydarpour Reza Malekzadeh Mohsen Naghavi Mohammad Ali Sahraian Sadaf G. Sepanlou Arash Tehrani-Banihashemi Reza Majdzadeh Valery L. Feigin Theo Vos Ali H. Mokdad Christopher J. L. Murray |
| author_sort | Kia Vosoughi |
| collection | DOAJ |
| description | Abstract Objectives Using the findings of the Global Burden of Disease Study (GBD), we report the burden of primary headache disorders in the Eastern Mediterranean Region (EMR) from 1990 to 2016. Methods We modelled headache disorders using DisMod-MR 2.1 Bayesian meta-regression tool to ensure consistency between prevalence, incidence, and remission. Years lived with disability (YLDs) were calculated by multiplying prevalence and disability weight (DW) of migraine and tension-type headache (TTH). We assumed primary headache disorders as non-fatal, so their YLD is equal to disability-adjusted life years (DALYs). Results Migraine and TTH were the second and twentieth leading causes of YLDs in EMR. Between 1990 and 2016, the absolute YLD numbers of migraine and TTH increased from 2.3 million (95% uncertainty interval (UI): 1.5–3.2) to 4.7 million (95%UI: 3–6.5) and from 383 thousand (95%UI: 240–562) to 816 thousand (95%UI: 516–1221), respectively. During the same period, age-standardised YLD rates of migraine and TTH in EMR increased by 0.7% and 2.5%, respectively, in comparison to a small decrease in the global rates (0.2% decrease in migraine and TTH). The bulk of burden due to headache occurred in the 30–49 year age group, with a peak at ages 35–44 years. The age-standardised YLD rates of both headache disorders were higher in women with female to male ratio of 1.69 for migraine and 1.38 for TTH. All countries of the EMR except for Somalia and Djibouti had higher age-standardised YLD rates for migraine and TTH in compare to the global rates. Libya and Saudi Arabia had the highest increase in age-standardised YLD rates of migraine and TTH, respectively. Conclusion The findings of this study show that primary headache disorders are a major and a growing cause of disability in EMR. Since 1990, burden of primary headache disorders has constantly been higher in EMR compared to rest of the world, which indicates that health systems in EMR must focus further on developing and implementing preventive and management strategies to control headache. |
| first_indexed | 2024-12-12T18:14:06Z |
| format | Article |
| id | doaj.art-ccdd40cedccd4440bf8c1ff455d0d5a8 |
| institution | Directory Open Access Journal |
| issn | 1129-2369 1129-2377 |
| language | English |
| last_indexed | 2024-12-12T18:14:06Z |
| publishDate | 2019-04-01 |
| publisher | BMC |
| record_format | Article |
| series | The Journal of Headache and Pain |
| spelling | doaj.art-ccdd40cedccd4440bf8c1ff455d0d5a82022-12-22T00:16:19ZengBMCThe Journal of Headache and Pain1129-23691129-23772019-04-0120111310.1186/s10194-019-0990-3The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016Kia Vosoughi0Lars Jacob Stovner1Timothy J. Steiner2Maziar Moradi-Lakeh3Seyed-Mohammad Fereshtehnejad4Farshad Farzadfar5Pouria Heydarpour6Reza Malekzadeh7Mohsen Naghavi8Mohammad Ali Sahraian9Sadaf G. Sepanlou10Arash Tehrani-Banihashemi11Reza Majdzadeh12Valery L. Feigin13Theo Vos14Ali H. Mokdad15Christopher J. L. Murray16Preventive Medicine and Public Health Research Center, Iran University of Medical SciencesDepartment of Neuromedicine and Movement Science (INB), Norwegian University of Science and Technology (NTNU)Department of Neuromedicine and Movement Science (INB), Norwegian University of Science and Technology (NTNU)Preventive Medicine and Public Health Research Center, Iran University of Medical SciencesDivision of Neurology, Department of Medicine, The Ottawa Hospital, University of OttawaNon-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical SciencesMultiple Sclerosis Research Center, Tehran University of Medical SciencesDigestive Disease Research Institute, Tehran University of Medical SciencesDepartment of Health Metrics Sciences, University of WashingtonMultiple Sclerosis Research Center, Tehran University of Medical SciencesDigestive Disease Research Institute, Tehran University of Medical SciencesPreventive Medicine and Public Health Research Center, Social Health Institute, Iran University of Medical SciencesKnowledge Utilization Research Center, Tehran University of Medical SciencesDepartment of Health Metrics Sciences, University of WashingtonDepartment of Health Metrics Sciences, University of WashingtonDepartment of Health Metrics Sciences, University of WashingtonDepartment of Health Metrics Sciences, University of WashingtonAbstract Objectives Using the findings of the Global Burden of Disease Study (GBD), we report the burden of primary headache disorders in the Eastern Mediterranean Region (EMR) from 1990 to 2016. Methods We modelled headache disorders using DisMod-MR 2.1 Bayesian meta-regression tool to ensure consistency between prevalence, incidence, and remission. Years lived with disability (YLDs) were calculated by multiplying prevalence and disability weight (DW) of migraine and tension-type headache (TTH). We assumed primary headache disorders as non-fatal, so their YLD is equal to disability-adjusted life years (DALYs). Results Migraine and TTH were the second and twentieth leading causes of YLDs in EMR. Between 1990 and 2016, the absolute YLD numbers of migraine and TTH increased from 2.3 million (95% uncertainty interval (UI): 1.5–3.2) to 4.7 million (95%UI: 3–6.5) and from 383 thousand (95%UI: 240–562) to 816 thousand (95%UI: 516–1221), respectively. During the same period, age-standardised YLD rates of migraine and TTH in EMR increased by 0.7% and 2.5%, respectively, in comparison to a small decrease in the global rates (0.2% decrease in migraine and TTH). The bulk of burden due to headache occurred in the 30–49 year age group, with a peak at ages 35–44 years. The age-standardised YLD rates of both headache disorders were higher in women with female to male ratio of 1.69 for migraine and 1.38 for TTH. All countries of the EMR except for Somalia and Djibouti had higher age-standardised YLD rates for migraine and TTH in compare to the global rates. Libya and Saudi Arabia had the highest increase in age-standardised YLD rates of migraine and TTH, respectively. Conclusion The findings of this study show that primary headache disorders are a major and a growing cause of disability in EMR. Since 1990, burden of primary headache disorders has constantly been higher in EMR compared to rest of the world, which indicates that health systems in EMR must focus further on developing and implementing preventive and management strategies to control headache.http://link.springer.com/article/10.1186/s10194-019-0990-3Primary headacheMigraineTension-type headacheBurdenPrevalenceYears lived with disability (YLDs) |
| spellingShingle | Kia Vosoughi Lars Jacob Stovner Timothy J. Steiner Maziar Moradi-Lakeh Seyed-Mohammad Fereshtehnejad Farshad Farzadfar Pouria Heydarpour Reza Malekzadeh Mohsen Naghavi Mohammad Ali Sahraian Sadaf G. Sepanlou Arash Tehrani-Banihashemi Reza Majdzadeh Valery L. Feigin Theo Vos Ali H. Mokdad Christopher J. L. Murray The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016 The Journal of Headache and Pain Primary headache Migraine Tension-type headache Burden Prevalence Years lived with disability (YLDs) |
| title | The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016 |
| title_full | The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016 |
| title_fullStr | The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016 |
| title_full_unstemmed | The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016 |
| title_short | The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: findings from the Global Burden of Disease study 2016 |
| title_sort | burden of headache disorders in the eastern mediterranean region 1990 2016 findings from the global burden of disease study 2016 |
| topic | Primary headache Migraine Tension-type headache Burden Prevalence Years lived with disability (YLDs) |
| url | http://link.springer.com/article/10.1186/s10194-019-0990-3 |
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