Effectiveness and practical uses of 23-valent pneumococcal polysaccharide vaccine in healthy and special populations
Streptococcus pneumonia (S. pneumoniae) is responsible for significant morbidity and mortality throughout the world. The 23-valent pneumococcal polysaccharide vaccines (PPV23) have been widely used for many years, but challenges are remaining in some respects, especially for its effectiveness among...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2018-04-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2017.1409316 |
| _version_ | 1797677573562433536 |
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| author | Yang Wang Jingxin Li Yuxiao Wang Wei Gu Fengcai Zhu |
| author_facet | Yang Wang Jingxin Li Yuxiao Wang Wei Gu Fengcai Zhu |
| author_sort | Yang Wang |
| collection | DOAJ |
| description | Streptococcus pneumonia (S. pneumoniae) is responsible for significant morbidity and mortality throughout the world. The 23-valent pneumococcal polysaccharide vaccines (PPV23) have been widely used for many years, but challenges are remaining in some respects, especially for its effectiveness among high-risk populations and older adults. This review aims to summarize recent clinical trials and studies of PPV23 vaccination among healthy people ≥ 2 years of age and those with high-risk conditions such as pregnant women, individuals with immunocompromising diseases and other chronic conditions, and provide health officials in China and other developing countries a comprehensive understanding of the current vaccination strategies for PPV23 and for the combined use of PPV23 and pneumococcal conjugate vaccines (PCVs) in adults. |
| first_indexed | 2024-03-11T22:46:07Z |
| format | Article |
| id | doaj.art-cce0888a1590418b9ef9b68221b18dab |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:46:07Z |
| publishDate | 2018-04-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-cce0888a1590418b9ef9b68221b18dab2023-09-22T08:17:53ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2018-04-011441003101210.1080/21645515.2017.14093161409316Effectiveness and practical uses of 23-valent pneumococcal polysaccharide vaccine in healthy and special populationsYang Wang0Jingxin Li1Yuxiao Wang2Wei Gu3Fengcai Zhu4School of Public Health, Southeast UniversityJiangsu Provincial Center for Disease Control and PreventionSchool of Public Health, Southeast UniversitySchool of Public Health, Nanjing Medical UniversityJiangsu Provincial Center for Disease Control and PreventionStreptococcus pneumonia (S. pneumoniae) is responsible for significant morbidity and mortality throughout the world. The 23-valent pneumococcal polysaccharide vaccines (PPV23) have been widely used for many years, but challenges are remaining in some respects, especially for its effectiveness among high-risk populations and older adults. This review aims to summarize recent clinical trials and studies of PPV23 vaccination among healthy people ≥ 2 years of age and those with high-risk conditions such as pregnant women, individuals with immunocompromising diseases and other chronic conditions, and provide health officials in China and other developing countries a comprehensive understanding of the current vaccination strategies for PPV23 and for the combined use of PPV23 and pneumococcal conjugate vaccines (PCVs) in adults.http://dx.doi.org/10.1080/21645515.2017.1409316clinical trialshigh-risk populationimmunization strategypneumococcal polysaccharide vaccinevaccine efficacy |
| spellingShingle | Yang Wang Jingxin Li Yuxiao Wang Wei Gu Fengcai Zhu Effectiveness and practical uses of 23-valent pneumococcal polysaccharide vaccine in healthy and special populations Human Vaccines & Immunotherapeutics clinical trials high-risk population immunization strategy pneumococcal polysaccharide vaccine vaccine efficacy |
| title | Effectiveness and practical uses of 23-valent pneumococcal polysaccharide vaccine in healthy and special populations |
| title_full | Effectiveness and practical uses of 23-valent pneumococcal polysaccharide vaccine in healthy and special populations |
| title_fullStr | Effectiveness and practical uses of 23-valent pneumococcal polysaccharide vaccine in healthy and special populations |
| title_full_unstemmed | Effectiveness and practical uses of 23-valent pneumococcal polysaccharide vaccine in healthy and special populations |
| title_short | Effectiveness and practical uses of 23-valent pneumococcal polysaccharide vaccine in healthy and special populations |
| title_sort | effectiveness and practical uses of 23 valent pneumococcal polysaccharide vaccine in healthy and special populations |
| topic | clinical trials high-risk population immunization strategy pneumococcal polysaccharide vaccine vaccine efficacy |
| url | http://dx.doi.org/10.1080/21645515.2017.1409316 |
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