Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil
Levels of persistent organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in the blood serum of people living and working in the urban area of greater Rio de Janeiro city. Blood samples from 33 volunteers (16 males, 17 females, 19-63 years old) were taken in January...
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Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
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| Series: | Cadernos de Saúde Pública |
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| Online Access: | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200017&lng=en&tlng=en |
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| author | Isabella Fernandes Delgado Heloisa H.C. Barretto Teresa A. Kussumi Irene Baptista Alleluia Cenira de A. Baggio Francisco José Roma Paumgartten |
| author_facet | Isabella Fernandes Delgado Heloisa H.C. Barretto Teresa A. Kussumi Irene Baptista Alleluia Cenira de A. Baggio Francisco José Roma Paumgartten |
| author_sort | Isabella Fernandes Delgado |
| collection | DOAJ |
| description | Levels of persistent organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in the blood serum of people living and working in the urban area of greater Rio de Janeiro city. Blood samples from 33 volunteers (16 males, 17 females, 19-63 years old) were taken in January 1999. OCP residues (op'DDT, pp'DDT, pp'DDD, pp'DDE, Aldrin, Dieldrin, Endrin, Heptachlor, Heptachlor-epoxide, alpha-, beta- and gamma-Hexachlorocyclo-hexane, Hexachlorobenzene) and PCBs (congeners: 28, 52, 101, 138, 153, 180) were extracted with n-hexane and analyzed by gas chromatography with electron capture detection. Except for pp'DDE (detection limit = 1.4µg/L) no other OCP residue was found in the samples. No PCB congener (detection limit = 2.0µg/L) was detected either. pp'DDE was found in 17 out of 33 samples in concentrations that ranged from 1.4 to 8.4 µg/L of serum or, on a fat basis, from 0.200 to 3.452 µg/g of serum lipids. Percentage of positive samples (%) and levels of pp'DDE (range of positive samples) increased from the youngest to the oldest group (<=29 yrs: 10%, 0.278µg/g; 30-39 yrs: 60%, 0.200-0.765µg/g; > or = 40 yrs: 77%, 0.257-3.452µg/g). |
| first_indexed | 2024-04-13T04:49:10Z |
| format | Article |
| id | doaj.art-cce301a46300435aaa92de34631d107b |
| institution | Directory Open Access Journal |
| issn | 0102-311X 1678-4464 |
| language | English |
| last_indexed | 2024-04-13T04:49:10Z |
| publisher | Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz |
| record_format | Article |
| series | Cadernos de Saúde Pública |
| spelling | doaj.art-cce301a46300435aaa92de34631d107b2022-12-22T03:01:44ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública0102-311X1678-4464182519524S0102-311X2002000200017Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, BrazilIsabella Fernandes Delgado0Heloisa H.C. Barretto1Teresa A. Kussumi2Irene Baptista Alleluia3Cenira de A. Baggio4Francisco José Roma Paumgartten5Fundação Oswaldo CruzInstituto Adolfo LutzInstituto Adolfo LutzInstituto Nacional de TecnologiaInstituto Nacional de TecnologiaFundação Oswaldo CruzLevels of persistent organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in the blood serum of people living and working in the urban area of greater Rio de Janeiro city. Blood samples from 33 volunteers (16 males, 17 females, 19-63 years old) were taken in January 1999. OCP residues (op'DDT, pp'DDT, pp'DDD, pp'DDE, Aldrin, Dieldrin, Endrin, Heptachlor, Heptachlor-epoxide, alpha-, beta- and gamma-Hexachlorocyclo-hexane, Hexachlorobenzene) and PCBs (congeners: 28, 52, 101, 138, 153, 180) were extracted with n-hexane and analyzed by gas chromatography with electron capture detection. Except for pp'DDE (detection limit = 1.4µg/L) no other OCP residue was found in the samples. No PCB congener (detection limit = 2.0µg/L) was detected either. pp'DDE was found in 17 out of 33 samples in concentrations that ranged from 1.4 to 8.4 µg/L of serum or, on a fat basis, from 0.200 to 3.452 µg/g of serum lipids. Percentage of positive samples (%) and levels of pp'DDE (range of positive samples) increased from the youngest to the oldest group (<=29 yrs: 10%, 0.278µg/g; 30-39 yrs: 60%, 0.200-0.765µg/g; > or = 40 yrs: 77%, 0.257-3.452µg/g).http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200017&lng=en&tlng=enorganic chemicalsddtpolychlorinated biphenylsendocrine disruptors |
| spellingShingle | Isabella Fernandes Delgado Heloisa H.C. Barretto Teresa A. Kussumi Irene Baptista Alleluia Cenira de A. Baggio Francisco José Roma Paumgartten Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil Cadernos de Saúde Pública organic chemicals ddt polychlorinated biphenyls endocrine disruptors |
| title | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
| title_full | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
| title_fullStr | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
| title_full_unstemmed | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
| title_short | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
| title_sort | serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of greater metropolitan rio de janeiro brazil |
| topic | organic chemicals ddt polychlorinated biphenyls endocrine disruptors |
| url | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200017&lng=en&tlng=en |
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