Role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopenia
Chronic obstructive pulmonary disease (COPD) is one of the most common chronic diseases in the elderly population and is characterized by persistent respiratory symptoms and airflow obstruction. During COPD progression, a variety of pulmonary and extrapulmonary complications develop, with sarcopenia...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2023.1214684/full |
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| author | Yayun Nan Yuting Zhou Yuting Zhou Ziyu Dai Ziyu Dai Ting Yan Pingping Zhong Pingping Zhong Fufeng Zhang Fufeng Zhang Qiong Chen Qiong Chen Linlin Peng Linlin Peng |
| author_facet | Yayun Nan Yuting Zhou Yuting Zhou Ziyu Dai Ziyu Dai Ting Yan Pingping Zhong Pingping Zhong Fufeng Zhang Fufeng Zhang Qiong Chen Qiong Chen Linlin Peng Linlin Peng |
| author_sort | Yayun Nan |
| collection | DOAJ |
| description | Chronic obstructive pulmonary disease (COPD) is one of the most common chronic diseases in the elderly population and is characterized by persistent respiratory symptoms and airflow obstruction. During COPD progression, a variety of pulmonary and extrapulmonary complications develop, with sarcopenia being one of the most common extrapulmonary complications. Factors that contribute to the pathogenesis of coexisting COPD and sarcopenia include systemic inflammation, hypoxia, hypercapnia, oxidative stress, protein metabolic imbalance, and myocyte mitochondrial dysfunction. These factors, individually or in concert, affect muscle function, resulting in decreased muscle mass and strength. The occurrence of sarcopenia severely affects the quality of life of patients with COPD, resulting in increased readmission rates, longer hospital admission, and higher mortality. In recent years, studies have found that oral supplementation with protein, micronutrients, fat, or a combination of nutritional supplements can improve the muscle strength and physical performance of these patients; some studies have also elucidated the possible underlying mechanisms. This review aimed to elucidate the role of nutrition among patients with coexisting COPD and sarcopenia. |
| first_indexed | 2024-03-12T16:57:08Z |
| format | Article |
| id | doaj.art-cce348e07c2b48689dc4bc117072d48c |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-03-12T16:57:08Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-cce348e07c2b48689dc4bc117072d48c2023-08-08T05:50:54ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2023-08-011010.3389/fnut.2023.12146841214684Role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopeniaYayun Nan0Yuting Zhou1Yuting Zhou2Ziyu Dai3Ziyu Dai4Ting Yan5Pingping Zhong6Pingping Zhong7Fufeng Zhang8Fufeng Zhang9Qiong Chen10Qiong Chen11Linlin Peng12Linlin Peng13Department of Ningxia Geriatrics Medical Center, Ningxia People’s Hospital, Yinchuan, ChinaDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Ningxia Geriatrics Medical Center, Ningxia People’s Hospital, Yinchuan, ChinaDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaChronic obstructive pulmonary disease (COPD) is one of the most common chronic diseases in the elderly population and is characterized by persistent respiratory symptoms and airflow obstruction. During COPD progression, a variety of pulmonary and extrapulmonary complications develop, with sarcopenia being one of the most common extrapulmonary complications. Factors that contribute to the pathogenesis of coexisting COPD and sarcopenia include systemic inflammation, hypoxia, hypercapnia, oxidative stress, protein metabolic imbalance, and myocyte mitochondrial dysfunction. These factors, individually or in concert, affect muscle function, resulting in decreased muscle mass and strength. The occurrence of sarcopenia severely affects the quality of life of patients with COPD, resulting in increased readmission rates, longer hospital admission, and higher mortality. In recent years, studies have found that oral supplementation with protein, micronutrients, fat, or a combination of nutritional supplements can improve the muscle strength and physical performance of these patients; some studies have also elucidated the possible underlying mechanisms. This review aimed to elucidate the role of nutrition among patients with coexisting COPD and sarcopenia.https://www.frontiersin.org/articles/10.3389/fnut.2023.1214684/fullnutritionchronic obstructive pulmonary diseasesarcopeniaskeletal muscledietary supplementstherapy |
| spellingShingle | Yayun Nan Yuting Zhou Yuting Zhou Ziyu Dai Ziyu Dai Ting Yan Pingping Zhong Pingping Zhong Fufeng Zhang Fufeng Zhang Qiong Chen Qiong Chen Linlin Peng Linlin Peng Role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopenia Frontiers in Nutrition nutrition chronic obstructive pulmonary disease sarcopenia skeletal muscle dietary supplements therapy |
| title | Role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopenia |
| title_full | Role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopenia |
| title_fullStr | Role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopenia |
| title_full_unstemmed | Role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopenia |
| title_short | Role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopenia |
| title_sort | role of nutrition in patients with coexisting chronic obstructive pulmonary disease and sarcopenia |
| topic | nutrition chronic obstructive pulmonary disease sarcopenia skeletal muscle dietary supplements therapy |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2023.1214684/full |
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