Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae
All eukaryotic organisms, single-celled or multi-cellular, produce a diverse array of natural anti-infective agents that, in addition to conventional antimicrobial peptides, also include proteins and other molecules often not regarded as part of the innate defences. Examples range from histones, fat...
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Format: | Article |
Language: | English |
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MDPI AG
2010-04-01
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Series: | Marine Drugs |
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Online Access: | http://www.mdpi.com/1660-3397/8/4/1213/ |
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author | Valerie J. Smith Andrew P. Desbois Elisabeth A. Dyrynda |
author_facet | Valerie J. Smith Andrew P. Desbois Elisabeth A. Dyrynda |
author_sort | Valerie J. Smith |
collection | DOAJ |
description | All eukaryotic organisms, single-celled or multi-cellular, produce a diverse array of natural anti-infective agents that, in addition to conventional antimicrobial peptides, also include proteins and other molecules often not regarded as part of the innate defences. Examples range from histones, fatty acids, and other structural components of cells to pigments and regulatory proteins. These probably represent very ancient defence factors that have been re-used in new ways during evolution. This review discusses the nature, biological role in host protection and potential biotechnological uses of some of these compounds, focusing on those from fish, marine invertebrates and marine micro-algae. |
first_indexed | 2024-04-11T10:59:01Z |
format | Article |
id | doaj.art-cce8025673404fbe88f796e851f6211b |
institution | Directory Open Access Journal |
issn | 1660-3397 |
language | English |
last_indexed | 2024-04-11T10:59:01Z |
publishDate | 2010-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Marine Drugs |
spelling | doaj.art-cce8025673404fbe88f796e851f6211b2022-12-22T04:28:41ZengMDPI AGMarine Drugs1660-33972010-04-01841213126210.3390/md8041213Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algaeValerie J. SmithAndrew P. DesboisElisabeth A. DyryndaAll eukaryotic organisms, single-celled or multi-cellular, produce a diverse array of natural anti-infective agents that, in addition to conventional antimicrobial peptides, also include proteins and other molecules often not regarded as part of the innate defences. Examples range from histones, fatty acids, and other structural components of cells to pigments and regulatory proteins. These probably represent very ancient defence factors that have been re-used in new ways during evolution. This review discusses the nature, biological role in host protection and potential biotechnological uses of some of these compounds, focusing on those from fish, marine invertebrates and marine micro-algae.http://www.mdpi.com/1660-3397/8/4/1213/amphipathicityantimicrobial peptidesfatty acidsinnate defencepigments |
spellingShingle | Valerie J. Smith Andrew P. Desbois Elisabeth A. Dyrynda Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae Marine Drugs amphipathicity antimicrobial peptides fatty acids innate defence pigments |
title | Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae |
title_full | Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae |
title_fullStr | Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae |
title_full_unstemmed | Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae |
title_short | Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae |
title_sort | conventional and unconventional antimicrobials from fish marine invertebrates and micro algae |
topic | amphipathicity antimicrobial peptides fatty acids innate defence pigments |
url | http://www.mdpi.com/1660-3397/8/4/1213/ |
work_keys_str_mv | AT valeriejsmith conventionalandunconventionalantimicrobialsfromfishmarineinvertebratesandmicroalgae AT andrewpdesbois conventionalandunconventionalantimicrobialsfromfishmarineinvertebratesandmicroalgae AT elisabethadyrynda conventionalandunconventionalantimicrobialsfromfishmarineinvertebratesandmicroalgae |