Dynamic Biobanking for Advancing Breast Cancer Research

Longitudinal patient biospecimens and data advance breast cancer research through enabling precision medicine approaches for identifying risk, early diagnosis, improved disease management and targeted therapy. Cancer biobanks must evolve to provide not only access to high-quality annotated biospecim...

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Bibliographic Details
Main Authors: Maryam Abdollahyan, Emanuela Gadaleta, Millahat Asif, Jorge Oscanoa, Rachel Barrow-McGee, Samantha Jones, Louise J Jones, Claude Chelala
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/13/2/360
Description
Summary:Longitudinal patient biospecimens and data advance breast cancer research through enabling precision medicine approaches for identifying risk, early diagnosis, improved disease management and targeted therapy. Cancer biobanks must evolve to provide not only access to high-quality annotated biospecimens and rich associated data, but also the tools required to harness these data. We present the Breast Cancer Now Tissue Bank centre at the Barts Cancer Institute as an exemplar of a dynamic biobanking ecosystem that hosts and links longitudinal biospecimens and multimodal data including electronic health records, genomic and imaging data, offered alongside integrated data sharing and analytics tools. We demonstrate how such an ecosystem can inform precision medicine efforts in breast cancer research.
ISSN:2075-4426