Isolation and In Silico Prediction of Potential Drug-like Compounds with a New Dimeric Prenylated Quinolone Alkaloid from <i>Zanthoxylum rhetsa</i> (Roxb.) Root Extracts Targeted against SARS-CoV-2 (Mpro)

Isolation and In Silico Prediction of Potential Drug-like Compounds with a New Dimeric Prenylated Quinolone Alkaloid from <i>Zanthoxylum rhetsa</i> (Roxb.) Root Extracts Targeted against SARS-CoV-2 (Mpro)

A new dimeric prenylated quinolone alkaloid, named 2,11-didemethoxy-vepridimerine A, was isolated from the root bark of <i>Zanthoxylum rhetsa</i>, together with twelve known compounds. The structure of the new compound was elucidated on the basis of spectroscopic investigations (NMR and...

Full description

Bibliographic Details
Main Authors: Fatema Tuz Zohora, A. T. M. Zafrul Azam, Sinthyia Ahmed, Khondaker Miraz Rahman, Mohammad A. Halim, Md. Rafi Anwar, Md. Hossain Sohrab, Fatema Tabassum, Choudhury Mahmood Hasan, Monira Ahsan
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
<i>Zanthoxylum rhetsa</i>
2,11-didemethoxy-vepridimerine A
SARS-CoV-2 (Mpro)
2-quinolone
benzophenanthridine alkaloids
Online Access:https://www.mdpi.com/1420-3049/27/23/8191

Internet

https://www.mdpi.com/1420-3049/27/23/8191

Similar Items