Assessment of outer retinal thickness and function in mice after experimental optic nerve trauma

Assessment of outer retinal thickness and function in mice after experimental optic nerve trauma

Abstract Background Optic nerve trauma caused by crush injury is frequently used for investigating experimental treatments that protect retinal ganglion cells (RGCs) and induce axonal regrowth. Retaining outer retinal light responses is essential for therapeutic rescue of RGCs after injury. However,...

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Bibliographic Details
Main Authors: Karin Rose Lypka, Tal Carmy-Bennun, Kimberly N. Garces, Alexander W. Venanzi, Abigail S. Hackam
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Ophthalmology
Subjects:
Retinal ganglion cells (RGCs)
Optic nerve crush
Photoreceptors
Electroretinogram
Axon degeneration
Online Access:https://doi.org/10.1186/s12886-022-02737-9

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