Targeting the Synapse in Alzheimer’s Disease

Dynamic gain and loss of synapses is fundamental to healthy brain function. While Alzheimer’s Disease (AD) treatment strategies have largely focussed on beta-amyloid and tau protein pathologies, the synapse itself may also be a critical endpoint to consider regarding disease modification. Disruption...

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Bibliographic Details
Main Authors: Johanna Jackson, Enrique Jambrina, Jennifer Li, Hugh Marston, Fiona Menzies, Keith Phillips, Gary Gilmour
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00735/full