The hepatitis C virus modulates insulin signaling pathway in vitro promoting insulin resistance.

The hepatitis C virus modulates insulin signaling pathway in vitro promoting insulin resistance.

Insulin is critical for controlling energy functions including glucose and lipid metabolism. Insulin resistance seems to interact with hepatitis C promoting fibrosis progression and impairing sustained virological response to peginterferon and ribavirin. The main aim was to elucidate the direct effe...

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Bibliographic Details
Main Authors: José A del Campo, Marta García-Valdecasas, Lourdes Rojas, Ángela Rojas, Manuel Romero-Gómez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485021?pdf=render

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