Should Jehovah’s Witness patients be listed for heart transplantation?

This best evidence topic in Cardiac Surgery was written according to a structured protocol. The question addressed was: for [Jehovah’s Witness patients with end-stage heart failure] can these patients undergo a [heart transplantation] without an increased rate of mortality. Altogether, 133 papers we...

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Main Authors: Elsayed Elmistekawy, Thierry G. Mesana, Marc Ruel
Format: Article
Language:English
Published: SpringerOpen 2014-03-01
Series:The Egyptian Heart Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110260813001841
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author Elsayed Elmistekawy
Thierry G. Mesana
Marc Ruel
author_facet Elsayed Elmistekawy
Thierry G. Mesana
Marc Ruel
author_sort Elsayed Elmistekawy
collection DOAJ
description This best evidence topic in Cardiac Surgery was written according to a structured protocol. The question addressed was: for [Jehovah’s Witness patients with end-stage heart failure] can these patients undergo a [heart transplantation] without an increased rate of mortality. Altogether, 133 papers were found using the reported search strategy. Of those, 29 papers represented the best evidence to answer the clinical question. Five papers focusing on patients of the Jehovah’s Witness (JW) faith who had end-stage heart failure were published. Successful heart transplantation was performed in a total of seven patients without mortality, re-exploration or blood transfusion. One patient had left ventricular reduction surgery twice and another patient had bypass surgery several years after transplantation. Other successful organ transplantations were also reported, including lung, liver, kidney and pancreas in both adult and paediatric patients of the JW faith, with comparable mortality and morbidity to non-JW patients. A publication bias is likely; nevertheless, we conclude that although there are no large studies directly focused on heart transplantation in JW patients, a multidisciplinary team approach to such surgery can make it technically feasible and without an increased mortality risk in suitable candidates. Therefore, such patients may be considered for heart transplantation under selected and favourable circumstances.
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spelling doaj.art-ccf42b06850c42cfa24de77171d9a6352022-12-22T00:37:43ZengSpringerOpenThe Egyptian Heart Journal1110-26082014-03-016612310.1016/j.ehj.2013.12.065Should Jehovah’s Witness patients be listed for heart transplantation?Elsayed ElmistekawyThierry G. MesanaMarc RuelThis best evidence topic in Cardiac Surgery was written according to a structured protocol. The question addressed was: for [Jehovah’s Witness patients with end-stage heart failure] can these patients undergo a [heart transplantation] without an increased rate of mortality. Altogether, 133 papers were found using the reported search strategy. Of those, 29 papers represented the best evidence to answer the clinical question. Five papers focusing on patients of the Jehovah’s Witness (JW) faith who had end-stage heart failure were published. Successful heart transplantation was performed in a total of seven patients without mortality, re-exploration or blood transfusion. One patient had left ventricular reduction surgery twice and another patient had bypass surgery several years after transplantation. Other successful organ transplantations were also reported, including lung, liver, kidney and pancreas in both adult and paediatric patients of the JW faith, with comparable mortality and morbidity to non-JW patients. A publication bias is likely; nevertheless, we conclude that although there are no large studies directly focused on heart transplantation in JW patients, a multidisciplinary team approach to such surgery can make it technically feasible and without an increased mortality risk in suitable candidates. Therefore, such patients may be considered for heart transplantation under selected and favourable circumstances.http://www.sciencedirect.com/science/article/pii/S1110260813001841TransplantationJehovah’s Witness patientsBloodless cardiac surgeryBleeding Evidence-based medicine
spellingShingle Elsayed Elmistekawy
Thierry G. Mesana
Marc Ruel
Should Jehovah’s Witness patients be listed for heart transplantation?
The Egyptian Heart Journal
Transplantation
Jehovah’s Witness patients
Bloodless cardiac surgery
Bleeding Evidence-based medicine
title Should Jehovah’s Witness patients be listed for heart transplantation?
title_full Should Jehovah’s Witness patients be listed for heart transplantation?
title_fullStr Should Jehovah’s Witness patients be listed for heart transplantation?
title_full_unstemmed Should Jehovah’s Witness patients be listed for heart transplantation?
title_short Should Jehovah’s Witness patients be listed for heart transplantation?
title_sort should jehovah s witness patients be listed for heart transplantation
topic Transplantation
Jehovah’s Witness patients
Bloodless cardiac surgery
Bleeding Evidence-based medicine
url http://www.sciencedirect.com/science/article/pii/S1110260813001841
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