Heterologous production of the D-cycloserine intermediate O-acetyl-L-serine in a human type II pulmonary cell model

Abstract Tuberculosis (TB) is the second leading cause of death by a single infectious disease behind COVID-19. Despite a century of effort, the current TB vaccine does not effectively prevent pulmonary TB, promote herd immunity, or prevent transmission. Therefore, alternative approaches are needed....

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Bibliographic Details
Main Authors: Laurel Robbins, Ariane Balaram, Stefanie Dejneka, Matthew McMahon, Zarina Najibi, Peter Pawlowicz, William H. Conrad
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35632-4