Ocular Disorders in Renal Transplant Patients
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Knowledge E
2008-12-01
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| Series: | Journal of Ophthalmic & Vision Research |
| Online Access: | http://www.jovr.ir/index.php/jovr/article/view/41 |
| _version_ | 1811323899448655872 |
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| author | Farzan Kian-Ersi Shahram Taheri Mohammad Reza Akhlaghi |
| author_facet | Farzan Kian-Ersi Shahram Taheri Mohammad Reza Akhlaghi |
| author_sort | Farzan Kian-Ersi |
| collection | DOAJ |
| description | <!--[if gte mso 9]><xml> Normal 0 false false false MicrosoftInternetExplorer4 </xml><![endif]--><!--[if gte mso 9]><xml> </xml><![endif]--> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} </style> <![endif]--> <p>PURPOSE: To determine ocular findings in patients with renal transplants and to correlate them with clinical characteristics related to transplantation. METHODS: This cross-sectional study was performed on 150 patients who had received a renal transplant of at least three months' duration with serum creatinine levels < 3 mg/dl. All patients underwent a complete ophthalmologic examination. Clinical variables related to the transplant included cause of renal failure, duration of hemodialysis prior to transplantation and immunosuppressive regimen. RESULTS: Overall, 91 male and 59 female subjects with mean age of 39±17.7 years were included. At least one ocular abnormality could be detected in 89.3% including visual acuity less than 20/25 (48.6%), conjunctival degeneration in the palpebral fissure (36.6%), posterior subcapsular cataracts (24%), pinguecula (17.3%), retinal pigment epitheliopathy (14%), arteriovenous crossing changes (8.6%), proliferative diabetic retinopathy (6%), central serous chorioretinopathy and retinal vein occlusions (each in 3.3%), and non-proliferative diabetic retinopathy, optic nerve atrophy and diabetic macular edema (each in 2.7%). Abnormal ocular findings were not correlated with the underlying renal disorder or use of cyclosporine and prednisolone, however they were positively correlated with transplant duration, pre-transplant dialysis duration and azathioprine or mycophenolate mofetil consumption. CONCLUSION: Ocular disorders are frequent among renal transplant patients especially with older transplants and those with a longer period of pre-transplant hemodialysis.</p> |
| first_indexed | 2024-04-13T14:04:43Z |
| format | Article |
| id | doaj.art-ccfc3055541b4fdf9a38d66e0c56c290 |
| institution | Directory Open Access Journal |
| issn | 2008-2010 2008-322X |
| language | English |
| last_indexed | 2024-04-13T14:04:43Z |
| publishDate | 2008-12-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-ccfc3055541b4fdf9a38d66e0c56c2902022-12-22T02:43:57ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2008-12-01212327Ocular Disorders in Renal Transplant PatientsFarzan Kian-ErsiShahram TaheriMohammad Reza Akhlaghi<!--[if gte mso 9]><xml> Normal 0 false false false MicrosoftInternetExplorer4 </xml><![endif]--><!--[if gte mso 9]><xml> </xml><![endif]--> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} </style> <![endif]--> <p>PURPOSE: To determine ocular findings in patients with renal transplants and to correlate them with clinical characteristics related to transplantation. METHODS: This cross-sectional study was performed on 150 patients who had received a renal transplant of at least three months' duration with serum creatinine levels < 3 mg/dl. All patients underwent a complete ophthalmologic examination. Clinical variables related to the transplant included cause of renal failure, duration of hemodialysis prior to transplantation and immunosuppressive regimen. RESULTS: Overall, 91 male and 59 female subjects with mean age of 39±17.7 years were included. At least one ocular abnormality could be detected in 89.3% including visual acuity less than 20/25 (48.6%), conjunctival degeneration in the palpebral fissure (36.6%), posterior subcapsular cataracts (24%), pinguecula (17.3%), retinal pigment epitheliopathy (14%), arteriovenous crossing changes (8.6%), proliferative diabetic retinopathy (6%), central serous chorioretinopathy and retinal vein occlusions (each in 3.3%), and non-proliferative diabetic retinopathy, optic nerve atrophy and diabetic macular edema (each in 2.7%). Abnormal ocular findings were not correlated with the underlying renal disorder or use of cyclosporine and prednisolone, however they were positively correlated with transplant duration, pre-transplant dialysis duration and azathioprine or mycophenolate mofetil consumption. CONCLUSION: Ocular disorders are frequent among renal transplant patients especially with older transplants and those with a longer period of pre-transplant hemodialysis.</p>http://www.jovr.ir/index.php/jovr/article/view/41 |
| spellingShingle | Farzan Kian-Ersi Shahram Taheri Mohammad Reza Akhlaghi Ocular Disorders in Renal Transplant Patients Journal of Ophthalmic & Vision Research |
| title | Ocular Disorders in Renal Transplant Patients |
| title_full | Ocular Disorders in Renal Transplant Patients |
| title_fullStr | Ocular Disorders in Renal Transplant Patients |
| title_full_unstemmed | Ocular Disorders in Renal Transplant Patients |
| title_short | Ocular Disorders in Renal Transplant Patients |
| title_sort | ocular disorders in renal transplant patients |
| url | http://www.jovr.ir/index.php/jovr/article/view/41 |
| work_keys_str_mv | AT farzankianersi oculardisordersinrenaltransplantpatients AT shahramtaheri oculardisordersinrenaltransplantpatients AT mohammadrezaakhlaghi oculardisordersinrenaltransplantpatients |