The Functional Impact of Alternative Splicing in Cancer

The Functional Impact of Alternative Splicing in Cancer

Alternative splicing changes are frequently observed in cancer and are starting to be recognized as important signatures for tumor progression and therapy. However, their functional impact and relevance to tumorigenesis remain mostly unknown. We carried out a systematic analysis to characterize the...

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Bibliographic Details
Main Authors:	Héctor Climente-González, Eduard Porta-Pardo, Adam Godzik, Eduardo Eyras
Format:	Article
Language:	English
Published:	Elsevier 2017-08-01
Series:	Cell Reports
Subjects:	alternative splicing transcript isoforms isoform switch cancer protein domains protein-protein interactions networks cancer drivers TCGA
Online Access:	http://www.sciencedirect.com/science/article/pii/S221112471731104X

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