Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material
The aim of this study was to characterise the physicochemical and biocompatibility properties of biosynthetic bacterial cellulose (BC) as a potential wound dressing material. The moisture content, water vapour transmission rate (WVTR), thermal stability, cyto- and haemo-compatibility of BC were inve...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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University of Huddersfield Press
2018-07-01
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Series: | British Journal of Pharmacy |
Subjects: | |
Online Access: | https://www.bjpharm.org.uk/article/id/56/ |
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author | Abhishek Gupta Wan Li Low Stephen Britland Iza Radecka Claire Martin |
author_facet | Abhishek Gupta Wan Li Low Stephen Britland Iza Radecka Claire Martin |
author_sort | Abhishek Gupta |
collection | DOAJ |
description | The aim of this study was to characterise the physicochemical and biocompatibility properties of biosynthetic bacterial cellulose (BC) as a potential wound dressing material. The moisture content, water vapour transmission rate (WVTR), thermal stability, cyto- and haemo-compatibility of BC were investigated. Results indicated that the physicochemical properties of biosynthetic BC allow an optimum WVTR to be maintained for improved localised wound moisture levels, good thermal stability and excellent water imbibing capabilities. In vitro cytotoxicity and haemocompatibility confirmed the biocompatibility of BC and hence suitability of this material for further exploration into its’ application as a wound dressing material. |
first_indexed | 2024-03-13T09:58:01Z |
format | Article |
id | doaj.art-cd01bccc5ebb44d8abcbd8a3129bf047 |
institution | Directory Open Access Journal |
issn | 2058-8356 |
language | English |
last_indexed | 2024-03-13T09:58:01Z |
publishDate | 2018-07-01 |
publisher | University of Huddersfield Press |
record_format | Article |
series | British Journal of Pharmacy |
spelling | doaj.art-cd01bccc5ebb44d8abcbd8a3129bf0472023-05-23T14:28:43ZengUniversity of Huddersfield PressBritish Journal of Pharmacy2058-83562018-07-012210.5920/bjpharm.2017.27Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing materialAbhishek GuptaWan Li LowStephen BritlandIza RadeckaClaire MartinThe aim of this study was to characterise the physicochemical and biocompatibility properties of biosynthetic bacterial cellulose (BC) as a potential wound dressing material. The moisture content, water vapour transmission rate (WVTR), thermal stability, cyto- and haemo-compatibility of BC were investigated. Results indicated that the physicochemical properties of biosynthetic BC allow an optimum WVTR to be maintained for improved localised wound moisture levels, good thermal stability and excellent water imbibing capabilities. In vitro cytotoxicity and haemocompatibility confirmed the biocompatibility of BC and hence suitability of this material for further exploration into its’ application as a wound dressing material.https://www.bjpharm.org.uk/article/id/56/wound managementhydrogelsbacterial cellulose |
spellingShingle | Abhishek Gupta Wan Li Low Stephen Britland Iza Radecka Claire Martin Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material British Journal of Pharmacy wound management hydrogels bacterial cellulose |
title | Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material |
title_full | Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material |
title_fullStr | Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material |
title_full_unstemmed | Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material |
title_short | Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material |
title_sort | physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material |
topic | wound management hydrogels bacterial cellulose |
url | https://www.bjpharm.org.uk/article/id/56/ |
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