Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material

The aim of this study was to characterise the physicochemical and biocompatibility properties of biosynthetic bacterial cellulose (BC) as a potential wound dressing material. The moisture content, water vapour transmission rate (WVTR), thermal stability, cyto- and haemo-compatibility of BC were inve...

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Main Authors: Abhishek Gupta, Wan Li Low, Stephen Britland, Iza Radecka, Claire Martin
Format: Article
Language:English
Published: University of Huddersfield Press 2018-07-01
Series:British Journal of Pharmacy
Subjects:
Online Access:https://www.bjpharm.org.uk/article/id/56/
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author Abhishek Gupta
Wan Li Low
Stephen Britland
Iza Radecka
Claire Martin
author_facet Abhishek Gupta
Wan Li Low
Stephen Britland
Iza Radecka
Claire Martin
author_sort Abhishek Gupta
collection DOAJ
description The aim of this study was to characterise the physicochemical and biocompatibility properties of biosynthetic bacterial cellulose (BC) as a potential wound dressing material. The moisture content, water vapour transmission rate (WVTR), thermal stability, cyto- and haemo-compatibility of BC were investigated. Results indicated that the physicochemical properties of biosynthetic BC allow an optimum WVTR to be maintained for improved localised wound moisture levels, good thermal stability and excellent water imbibing capabilities. In vitro cytotoxicity and haemocompatibility confirmed the biocompatibility of BC and hence suitability of this material for further exploration into its’ application as a wound dressing material.
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spelling doaj.art-cd01bccc5ebb44d8abcbd8a3129bf0472023-05-23T14:28:43ZengUniversity of Huddersfield PressBritish Journal of Pharmacy2058-83562018-07-012210.5920/bjpharm.2017.27Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing materialAbhishek GuptaWan Li LowStephen BritlandIza RadeckaClaire MartinThe aim of this study was to characterise the physicochemical and biocompatibility properties of biosynthetic bacterial cellulose (BC) as a potential wound dressing material. The moisture content, water vapour transmission rate (WVTR), thermal stability, cyto- and haemo-compatibility of BC were investigated. Results indicated that the physicochemical properties of biosynthetic BC allow an optimum WVTR to be maintained for improved localised wound moisture levels, good thermal stability and excellent water imbibing capabilities. In vitro cytotoxicity and haemocompatibility confirmed the biocompatibility of BC and hence suitability of this material for further exploration into its’ application as a wound dressing material.https://www.bjpharm.org.uk/article/id/56/wound managementhydrogelsbacterial cellulose
spellingShingle Abhishek Gupta
Wan Li Low
Stephen Britland
Iza Radecka
Claire Martin
Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material
British Journal of Pharmacy
wound management
hydrogels
bacterial cellulose
title Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material
title_full Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material
title_fullStr Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material
title_full_unstemmed Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material
title_short Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material
title_sort physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material
topic wound management
hydrogels
bacterial cellulose
url https://www.bjpharm.org.uk/article/id/56/
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AT wanlilow physicochemicalcharacterisationofbiosyntheticbacterialcelluloseasapotentialwounddressingmaterial
AT stephenbritland physicochemicalcharacterisationofbiosyntheticbacterialcelluloseasapotentialwounddressingmaterial
AT izaradecka physicochemicalcharacterisationofbiosyntheticbacterialcelluloseasapotentialwounddressingmaterial
AT clairemartin physicochemicalcharacterisationofbiosyntheticbacterialcelluloseasapotentialwounddressingmaterial