Cost-Effective Fiber Optic Solutions for Biosensing
In the last years, optical fiber sensors have proven to be a reliable and versatile biosensing tool. Optical fiber biosensors (OFBs) are analytical devices that use optical fibers as transducers, with the advantages of being easily coated and biofunctionalized, allowing the monitorization of all fun...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/12/8/575 |
| _version_ | 1797432391139065856 |
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| author | Cátia Leitão Sónia O. Pereira Carlos Marques Nunzio Cennamo Luigi Zeni Madina Shaimerdenova Takhmina Ayupova Daniele Tosi |
| author_facet | Cátia Leitão Sónia O. Pereira Carlos Marques Nunzio Cennamo Luigi Zeni Madina Shaimerdenova Takhmina Ayupova Daniele Tosi |
| author_sort | Cátia Leitão |
| collection | DOAJ |
| description | In the last years, optical fiber sensors have proven to be a reliable and versatile biosensing tool. Optical fiber biosensors (OFBs) are analytical devices that use optical fibers as transducers, with the advantages of being easily coated and biofunctionalized, allowing the monitorization of all functionalization and detection in real-time, as well as being small in size and geometrically flexible, thus allowing device miniaturization and portability for point-of-care (POC) testing. Knowing the potential of such biosensing tools, this paper reviews the reported OFBs which are, at the moment, the most cost-effective. Different fiber configurations are highlighted, namely, end-face reflected, unclad, D- and U-shaped, tips, ball resonators, tapered, light-diffusing, and specialty fibers. Packaging techniques to enhance OFBs’ application in the medical field, namely for implementing in subcutaneous, percutaneous, and endoscopic operations as well as in wearable structures, are presented and discussed. Interrogation approaches of OFBs using smartphones’ hardware are a great way to obtain cost-effective sensing approaches. In this review paper, different architectures of such interrogation methods and their respective applications are presented. Finally, the application of OFBs in monitoring three crucial fields of human life and wellbeing are reported: detection of cancer biomarkers, detection of cardiovascular biomarkers, and environmental monitoring. |
| first_indexed | 2024-03-09T10:00:48Z |
| format | Article |
| id | doaj.art-cd05868c2df84b25bdbd8ca7cc251d91 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T10:00:48Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-cd05868c2df84b25bdbd8ca7cc251d912023-12-01T23:29:57ZengMDPI AGBiosensors2079-63742022-07-0112857510.3390/bios12080575Cost-Effective Fiber Optic Solutions for BiosensingCátia Leitão0Sónia O. Pereira1Carlos Marques2Nunzio Cennamo3Luigi Zeni4Madina Shaimerdenova5Takhmina Ayupova6Daniele Tosi7i3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugali3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugali3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Engineering, University of Campania Luigi Vanvitelli, Via Roma 29, 81031 Aversa, ItalyDepartment of Engineering, University of Campania Luigi Vanvitelli, Via Roma 29, 81031 Aversa, ItalySchool of Engineering and Digital Sciences, Nazarbayev University, Nur-Sultan 010000, KazakhstanSchool of Engineering and Digital Sciences, Nazarbayev University, Nur-Sultan 010000, KazakhstanSchool of Engineering and Digital Sciences, Nazarbayev University, Nur-Sultan 010000, KazakhstanIn the last years, optical fiber sensors have proven to be a reliable and versatile biosensing tool. Optical fiber biosensors (OFBs) are analytical devices that use optical fibers as transducers, with the advantages of being easily coated and biofunctionalized, allowing the monitorization of all functionalization and detection in real-time, as well as being small in size and geometrically flexible, thus allowing device miniaturization and portability for point-of-care (POC) testing. Knowing the potential of such biosensing tools, this paper reviews the reported OFBs which are, at the moment, the most cost-effective. Different fiber configurations are highlighted, namely, end-face reflected, unclad, D- and U-shaped, tips, ball resonators, tapered, light-diffusing, and specialty fibers. Packaging techniques to enhance OFBs’ application in the medical field, namely for implementing in subcutaneous, percutaneous, and endoscopic operations as well as in wearable structures, are presented and discussed. Interrogation approaches of OFBs using smartphones’ hardware are a great way to obtain cost-effective sensing approaches. In this review paper, different architectures of such interrogation methods and their respective applications are presented. Finally, the application of OFBs in monitoring three crucial fields of human life and wellbeing are reported: detection of cancer biomarkers, detection of cardiovascular biomarkers, and environmental monitoring.https://www.mdpi.com/2079-6374/12/8/575POC monitoringsmartphone optical biosensorsoptical interrogation methodscancer biomarkerscardiovascular biomarkersenvironmental monitoring |
| spellingShingle | Cátia Leitão Sónia O. Pereira Carlos Marques Nunzio Cennamo Luigi Zeni Madina Shaimerdenova Takhmina Ayupova Daniele Tosi Cost-Effective Fiber Optic Solutions for Biosensing Biosensors POC monitoring smartphone optical biosensors optical interrogation methods cancer biomarkers cardiovascular biomarkers environmental monitoring |
| title | Cost-Effective Fiber Optic Solutions for Biosensing |
| title_full | Cost-Effective Fiber Optic Solutions for Biosensing |
| title_fullStr | Cost-Effective Fiber Optic Solutions for Biosensing |
| title_full_unstemmed | Cost-Effective Fiber Optic Solutions for Biosensing |
| title_short | Cost-Effective Fiber Optic Solutions for Biosensing |
| title_sort | cost effective fiber optic solutions for biosensing |
| topic | POC monitoring smartphone optical biosensors optical interrogation methods cancer biomarkers cardiovascular biomarkers environmental monitoring |
| url | https://www.mdpi.com/2079-6374/12/8/575 |
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