Murine Models for Trypanosoma brucei gambiense disease progression--from silent to chronic infections and early brain tropism.

Murine Models for Trypanosoma brucei gambiense disease progression--from silent to chronic infections and early brain tropism.

Human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense remains highly prevalent in west and central Africa and is lethal if left untreated. The major problem is that the disease often evolves toward chronic or asymptomatic forms with low and fluctuating parasitaemia producing app...

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Bibliographic Details
Main Authors: Christiane Giroud, Florence Ottones, Virginie Coustou, Denis Dacheux, Nicolas Biteau, Benjamin Miezan, Nick Van Reet, Mark Carrington, Felix Doua, Théo Baltz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2728506?pdf=render

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