CRISPR-Cas9-mediated disruption of B2M and CIITA genes eliminates HLA class I and II expression in human induced pluripotent stem cells (MUSIi001-A-2)
Cell-based therapy offers great promise for treating degenerative diseases. Although autologous cell-based therapy is ideal, it may be impractical due to the high manufacturing cost and long production time. Allogeneic cell-based therapy offers a more cost-effective alternative; however, the risk of...
Auteurs principaux: | Nontaphat Thongsin, Siriwal Suwanpitak, Methichit Wattanapanitch |
---|---|
Format: | Article |
Langue: | English |
Publié: |
Elsevier
2023-09-01
|
Collection: | Stem Cell Research |
Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S1873506123001241 |
Documents similaires
-
Generation of a homozygous TIGIT gene knockout (TIGIT−/−) human iPSC line (MUSIi001-A-3) using CRISPR/Cas9 system
par: Jakkrapatra Srisantitham, et autres
Publié: (2024-12-01) -
Phenotypic and transcriptomic profiling of induced pluripotent stem cell (iPSC)-derived NK cells and their cytotoxicity against cancers
par: Nontaphat Thongsin, et autres
Publié: (2024-11-01) -
A precise gene delivery approach for human induced pluripotent stem cells using Cas9 RNP complex and recombinant AAV6 donor vectors.
par: Koollawat Chupradit, et autres
Publié: (2022-01-01) -
Generation of an induced pluripotent stem cell line (MUSIi015-A) from a diabetic patient carrying mutations in ZYG11A (p.L475P) and GATA6 (p.E51K)
par: Siriwal Suwanpitak, et autres
Publié: (2022-08-01) -
A three-dimensional immune-oncology model for studying in vitro primary human NK cell cytotoxic activity.
par: Nontaphat Thongsin, et autres
Publié: (2022-01-01)