CRISPR-Cas9-mediated disruption of B2M and CIITA genes eliminates HLA class I and II expression in human induced pluripotent stem cells (MUSIi001-A-2)

Cell-based therapy offers great promise for treating degenerative diseases. Although autologous cell-based therapy is ideal, it may be impractical due to the high manufacturing cost and long production time. Allogeneic cell-based therapy offers a more cost-effective alternative; however, the risk of...

Полное описание

Библиографические подробности
Главные авторы: Nontaphat Thongsin, Siriwal Suwanpitak, Methichit Wattanapanitch
Формат: Статья
Язык:English
Опубликовано: Elsevier 2023-09-01
Серии:Stem Cell Research
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1873506123001241