Atrial depolarization abnormalities in pulmonary sarcoidosis
Abstract Background Cardiac sarcoidosis, often manifested as sudden death, can be the first manifestation of sarcoidosis. Since 12-lead electrocardiogram (ECG) is recommended as an initial screening tool for cardiac sarcoidosis, the recognition of subtle abnormalities assumes utmost significance. Th...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-10-01
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| Series: | The Egyptian Heart Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43044-022-00312-7 |
| _version_ | 1817979631488204800 |
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| author | Amal Paul Akhil Paul Immanuel Subhash Bijesh Yadav John Roshan Jacob D. J. Christopher T. Balamugesh |
| author_facet | Amal Paul Akhil Paul Immanuel Subhash Bijesh Yadav John Roshan Jacob D. J. Christopher T. Balamugesh |
| author_sort | Amal Paul |
| collection | DOAJ |
| description | Abstract Background Cardiac sarcoidosis, often manifested as sudden death, can be the first manifestation of sarcoidosis. Since 12-lead electrocardiogram (ECG) is recommended as an initial screening tool for cardiac sarcoidosis, the recognition of subtle abnormalities assumes utmost significance. The objective of this study was to identify the electrocardiographic abnormalities in patients with pulmonary sarcoidosis. Results A detailed analysis of 12-lead ECGs obtained from sixty patients with histopathologically proven pulmonary sarcoidosis and no overt cardiac involvement was done. The findings were compared with those of an age-matched control group. Varying degrees of intraventricular conduction defects were common in the study group [67%], as well as the control group [57%] [P = 0.23]. There was a higher prevalence of biphasic P wave [P = 0.003] and bifid P wave [P = 0.029] in lead III and rsr’ in lead aVF [P = 0.03] in the study group as compared to the control group. Conclusions Our study demonstrates a greater prevalence of subtle ECG abnormalities in patients with pulmonary sarcoidosis as compared to patients with other forms of pulmonary disease. Atrial depolarization abnormalities were commoner in patients with pulmonary sarcoidosis. |
| first_indexed | 2024-04-13T22:45:00Z |
| format | Article |
| id | doaj.art-cd121419a72b4c7cbbe1885a3c813a63 |
| institution | Directory Open Access Journal |
| issn | 2090-911X |
| language | English |
| last_indexed | 2024-04-13T22:45:00Z |
| publishDate | 2022-10-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Heart Journal |
| spelling | doaj.art-cd121419a72b4c7cbbe1885a3c813a632022-12-22T02:26:28ZengSpringerOpenThe Egyptian Heart Journal2090-911X2022-10-017411610.1186/s43044-022-00312-7Atrial depolarization abnormalities in pulmonary sarcoidosisAmal Paul0Akhil Paul1Immanuel Subhash2Bijesh Yadav3John Roshan Jacob4D. J. Christopher5T. Balamugesh6Department of Cardiology, Christian Medical College and Hospital (CMCH)Department of Pulmonary Medicine, Christian Medical College and Hospital (CMCH)Department of Pulmonary Medicine, Christian Medical College and Hospital (CMCH)Department of Biostatistics, Christian Medical College and Hospital (CMCH)Department of Cardiology and Cardiac Electrophysiology, Christian Medical College and Hospital (CMCH)Department of Pulmonary Medicine, Christian Medical College and Hospital (CMCH)Department of Pulmonary Medicine, Christian Medical College and Hospital (CMCH)Abstract Background Cardiac sarcoidosis, often manifested as sudden death, can be the first manifestation of sarcoidosis. Since 12-lead electrocardiogram (ECG) is recommended as an initial screening tool for cardiac sarcoidosis, the recognition of subtle abnormalities assumes utmost significance. The objective of this study was to identify the electrocardiographic abnormalities in patients with pulmonary sarcoidosis. Results A detailed analysis of 12-lead ECGs obtained from sixty patients with histopathologically proven pulmonary sarcoidosis and no overt cardiac involvement was done. The findings were compared with those of an age-matched control group. Varying degrees of intraventricular conduction defects were common in the study group [67%], as well as the control group [57%] [P = 0.23]. There was a higher prevalence of biphasic P wave [P = 0.003] and bifid P wave [P = 0.029] in lead III and rsr’ in lead aVF [P = 0.03] in the study group as compared to the control group. Conclusions Our study demonstrates a greater prevalence of subtle ECG abnormalities in patients with pulmonary sarcoidosis as compared to patients with other forms of pulmonary disease. Atrial depolarization abnormalities were commoner in patients with pulmonary sarcoidosis.https://doi.org/10.1186/s43044-022-00312-7SarcoidosisElectrocardiogram (ECG)Biphasic PCardiac sarcoidosisAtrial depolarization |
| spellingShingle | Amal Paul Akhil Paul Immanuel Subhash Bijesh Yadav John Roshan Jacob D. J. Christopher T. Balamugesh Atrial depolarization abnormalities in pulmonary sarcoidosis The Egyptian Heart Journal Sarcoidosis Electrocardiogram (ECG) Biphasic P Cardiac sarcoidosis Atrial depolarization |
| title | Atrial depolarization abnormalities in pulmonary sarcoidosis |
| title_full | Atrial depolarization abnormalities in pulmonary sarcoidosis |
| title_fullStr | Atrial depolarization abnormalities in pulmonary sarcoidosis |
| title_full_unstemmed | Atrial depolarization abnormalities in pulmonary sarcoidosis |
| title_short | Atrial depolarization abnormalities in pulmonary sarcoidosis |
| title_sort | atrial depolarization abnormalities in pulmonary sarcoidosis |
| topic | Sarcoidosis Electrocardiogram (ECG) Biphasic P Cardiac sarcoidosis Atrial depolarization |
| url | https://doi.org/10.1186/s43044-022-00312-7 |
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