LDLR, LRP1, and Megalin redundantly participate in the uptake of Clostridium novyi alpha-toxin

LDLR, LRP1, and Megalin redundantly participate in the uptake of Clostridium novyi alpha-toxin

Clostridium novyi alpha-toxin (Tcnα) also uses LRP1 and Megalin as cellular entry receptors besides LDLR, and this might be a response to cell-type dependent receptor availability for the exotoxin.

Bibliographic Details
Main Authors:	Yao Zhou, Danyang Li, Diyin Li, Aizhong Chen, Liuqing He, Jianhua Luo, Liang Tao
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-09-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-022-03873-0

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