Latent Tuberculosis among Persons at Risk for Infection with HIV, Tijuana, Mexico

Because there is little routine tuberculosis (TB) screening in Mexico, the prevalence of latent TB infection (LTBI) is unknown. In the context of an increasing HIV epidemic in Tijuana, Mexico, understanding prevalence of LTBI to anticipate emergence of increased LTBI reactivation is critical. Theref...

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Bibliographic Details
Main Authors: Richard S. Garfein, Rafael Laniado-Laborin, Timothy C. Rodwell, Remedios Lozada, Robert G. Deiss, Jose Luis Burgos, Jazmine Cuevas-Mota, Paris Cerecer, Kathleen Moser, Maria Luisa Volker, Steffanie A. Strathdee
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2010-05-01
Series:Emerging Infectious Diseases
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Online Access:https://wwwnc.cdc.gov/eid/article/16/5/09-1446_article
Description
Summary:Because there is little routine tuberculosis (TB) screening in Mexico, the prevalence of latent TB infection (LTBI) is unknown. In the context of an increasing HIV epidemic in Tijuana, Mexico, understanding prevalence of LTBI to anticipate emergence of increased LTBI reactivation is critical. Therefore, we recruited injection drug users, noninjection drug users, female sex workers, and homeless persons for a study involving risk assessment, rapid HIV testing, and TB screening. Of 503 participants, the overall prevalences of TB infection, HIV infection, and TB/HIV co-infection were 57%, 4.2%, and 2.2%, respectively; no significant differences by risk group (p>0.05) were observed. Two participants had TB (prevalence 398/100,000). Incarceration in Mexico (odds ratio [OR] 2.28), age (OR 1.03 per year), and years lived in Tijuana (OR 1.02 per year) were independently associated with TB infection (p<0.05). Frequent LTBI in marginalized persons may lead to increases in TB as HIV spreads.
ISSN:1080-6040
1080-6059