Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding
Abstract Background Giant cell tumors of the mobile spine invasion of the adjacent vertebrae are an ignored imaging finding. Methods Nine patients with giant cell tumors of the mobile spine with invasion of the adjacent vertebrae confirmed by pathology were enrolled. Eight patients had pure giant ce...
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| Format: | Article |
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BMC
2021-08-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-021-04610-0 |
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| author | Gang Jiang Ling-Ling Sun Yong-Jun Ye Zhi-Tao Yang Qing-lian Ji Jing Pang Chuan-Ping Gao |
| author_facet | Gang Jiang Ling-Ling Sun Yong-Jun Ye Zhi-Tao Yang Qing-lian Ji Jing Pang Chuan-Ping Gao |
| author_sort | Gang Jiang |
| collection | DOAJ |
| description | Abstract Background Giant cell tumors of the mobile spine invasion of the adjacent vertebrae are an ignored imaging finding. Methods Nine patients with giant cell tumors of the mobile spine with invasion of the adjacent vertebrae confirmed by pathology were enrolled. Eight patients had pure giant cell tumors (GCTs), while one patient also had an aneurysmal bone cyst. All patients underwent conventional computed tomography, three-dimensional reconstruction, and conventional magnetic resonance imaging, while seven patients also underwent post-contrast magnetic resonance imaging. Results All patients showed GCTs of the mobile spine that arose from the vertebral body and extended to the vertebral arch. The tumors showed soft-tissue attenuation with no evidence of a mineralized matrix. Pathological fracture was seen in five patients. The margin of the original tumor showed partial sclerosis in four patients and involved an adjacent vertebral body with a sclerotic rim in two patients. The tumors showed a homogeneous and similar signal intensity to the normal spinal cord on T1WI (T1-weighted image) in five patients. The cystic area of the tumors was hyperintense on T2WI in the remaining four patients, while one patient showed hemorrhage that was hyperintense on T1WI. The solid components of the GCTs show marked enhancement in all cases, while the cystic area of the tumors was observed without enhancement on contrast-enhanced images in four patients. Bone destruction of the adjacent vertebral body showed a homogeneous signal on T1WI and T2WI and marked enhancement on contrast-enhanced images. Conclusions Giant cell tumors of the mobile spine with invasion into adjacent vertebrae are an unusual imaging finding. Radiologists should be familiar with this imaging characteristic. |
| first_indexed | 2024-12-17T04:48:01Z |
| format | Article |
| id | doaj.art-cd20cbf7df514812af7574242bfa5991 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-17T04:48:01Z |
| publishDate | 2021-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-cd20cbf7df514812af7574242bfa59912022-12-21T22:03:01ZengBMCBMC Musculoskeletal Disorders1471-24742021-08-012211710.1186/s12891-021-04610-0Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging findingGang Jiang0Ling-Ling Sun1Yong-Jun Ye2Zhi-Tao Yang3Qing-lian Ji4Jing Pang5Chuan-Ping Gao6Department of Radiology, The affiliated hospital of Qingdao UniversityDepartment of Pathology, The affiliated hospital of Qingdao UniversityDepartment of Radiology, Lishui Hospital of Zhejiang UniversityDepartment of Radiology, The affiliated hospital of Qingdao UniversityDepartment of Radiology, The affiliated hospital of Qingdao UniversityDepartment of Radiology, The affiliated hospital of Qingdao UniversityDepartment of Radiology, The affiliated hospital of Qingdao UniversityAbstract Background Giant cell tumors of the mobile spine invasion of the adjacent vertebrae are an ignored imaging finding. Methods Nine patients with giant cell tumors of the mobile spine with invasion of the adjacent vertebrae confirmed by pathology were enrolled. Eight patients had pure giant cell tumors (GCTs), while one patient also had an aneurysmal bone cyst. All patients underwent conventional computed tomography, three-dimensional reconstruction, and conventional magnetic resonance imaging, while seven patients also underwent post-contrast magnetic resonance imaging. Results All patients showed GCTs of the mobile spine that arose from the vertebral body and extended to the vertebral arch. The tumors showed soft-tissue attenuation with no evidence of a mineralized matrix. Pathological fracture was seen in five patients. The margin of the original tumor showed partial sclerosis in four patients and involved an adjacent vertebral body with a sclerotic rim in two patients. The tumors showed a homogeneous and similar signal intensity to the normal spinal cord on T1WI (T1-weighted image) in five patients. The cystic area of the tumors was hyperintense on T2WI in the remaining four patients, while one patient showed hemorrhage that was hyperintense on T1WI. The solid components of the GCTs show marked enhancement in all cases, while the cystic area of the tumors was observed without enhancement on contrast-enhanced images in four patients. Bone destruction of the adjacent vertebral body showed a homogeneous signal on T1WI and T2WI and marked enhancement on contrast-enhanced images. Conclusions Giant cell tumors of the mobile spine with invasion into adjacent vertebrae are an unusual imaging finding. Radiologists should be familiar with this imaging characteristic.https://doi.org/10.1186/s12891-021-04610-0Giant cell tumorsMobile spineAdjacent vertebrae invasionComputed tomographyMagnetic resonance imaging |
| spellingShingle | Gang Jiang Ling-Ling Sun Yong-Jun Ye Zhi-Tao Yang Qing-lian Ji Jing Pang Chuan-Ping Gao Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding BMC Musculoskeletal Disorders Giant cell tumors Mobile spine Adjacent vertebrae invasion Computed tomography Magnetic resonance imaging |
| title | Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding |
| title_full | Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding |
| title_fullStr | Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding |
| title_full_unstemmed | Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding |
| title_short | Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding |
| title_sort | giant cell tumors of the mobile spine with invasion of adjacent vertebrae an unusual imaging finding |
| topic | Giant cell tumors Mobile spine Adjacent vertebrae invasion Computed tomography Magnetic resonance imaging |
| url | https://doi.org/10.1186/s12891-021-04610-0 |
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