Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer

Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer

Abstract Background Epigenetic alterations are strongly associated with the development of cancer. The aim of this study was to identify epigenetic pattern in squamous cell lung cancer (LUSC) on a genome-wide scale. Results Here we performed DNA methylation profiling on 24 LUSC and paired non-tumor...

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Bibliographic Details
Main Authors: Yuan-Xiang Shi, Ying Wang, Xi Li, Wei Zhang, Hong-Hao Zhou, Ji-Ye Yin, Zhao-Qian Liu
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Genomics
Subjects:
Lung cancer
DNA methylation
Biomarker
Diagnosis
Epigenetics
Online Access:http://link.springer.com/article/10.1186/s12864-017-4223-3

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