A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs

A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs

Abstract Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide and presents pathologically with Lewy pathology and dopaminergic neurodegeneration. Lewy pathology contains aggregated α-synuclein (αSyn), a protein encoded by the SNCA gene which is also mutated or dupli...

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Bibliographic Details
Main Authors: Haley M. Geertsma, Zoe A. Fisk, Lillian Sauline, Alice Prigent, Kevin Kurgat, Steve M. Callaghan, aSCENT-PD Consortium, Michael X. Henderson, Maxime W. C. Rousseaux
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00672-8

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