MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction

Abstract Background Our study aim was to evaluate the therapeutic efficacy and mechanisms of miR-133-overexpressing mesenchymal stem cells (MSCs) on acute myocardial infarction. Methods Rat MSCs were isolated and purified by whole bone marrow adherent culturing. After transfection with the agomir or...

Full description

Bibliographic Details
Main Authors: Yueqiu Chen, Yunfeng Zhao, Weiqian Chen, Lincen Xie, Zhen-Ao Zhao, Junjie Yang, Yihuan Chen, Wei Lei, Zhenya Shen
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-017-0722-z