Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria

Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria

The prevalence of diabetes reaches epidemic proportions. Diabetes is the leading cause of end-stage kidney disease (ESKD) since 30–40% of diabetic patients develop diabetic nephropathy. Albuminuria and glomerular filtration rate used to assess kidney function are considered surrogate outcomes of chr...

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Bibliographic Details
Main Authors: Rajkishor Nishad, Vazeeha Tahaseen, Rajesh Kavvuri, Manga Motrapu, Ashish K Singh, Kiranmayi Peddi, Anil K Pasupulati
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Medicine
Subjects:
diabetic kidney disease
advanced glycation end-products
carboxy methyl lysine
podocytes
albuminuria
Introduction
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.685447/full

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