HCC development is associated to peripheral insulin resistance in a mouse model of NASH.

HCC development is associated to peripheral insulin resistance in a mouse model of NASH.

NAFLD is the most common liver disease worldwide but it is the potential evolution to NASH and eventually to hepatocellular carcinoma (HCC), even in the absence of cirrhosis, that makes NAFLD of such clinical importance.we aimed to create a mouse model reproducing the pathological spectrum of NAFLD...

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Bibliographic Details
Main Authors: Samuele De Minicis, Laura Agostinelli, Chiara Rychlicki, Gian Pio Sorice, Stefania Saccomanno, Cinzia Candelaresi, Andrea Giaccari, Luciano Trozzi, Irene Pierantonelli, Eleonora Mingarelli, Marco Marzioni, Giovanna Muscogiuri, Melania Gaggini, Antonio Benedetti, Amalia Gastaldelli, Maria Guido, Gianluca Svegliati-Baroni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4031080?pdf=render

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http://europepmc.org/articles/PMC4031080?pdf=render

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