Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum)
Bats are known reservoirs of viral zoonoses. We report genetic characterization of a bat rotavirus (Bat/KE4852/07) detected in the feces of a straw-colored fruit bat (Eidolon helvum). Six bat rotavirus genes (viral protein [VP] 2, VP6, VP7, nonstructural protein [NSP] 2, NSP3, and NSP5) shared ances...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2010-12-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/16/12/10-1089_article |
| _version_ | 1828520344311300096 |
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| author | Mathew D. Esona Slavica Mijatovic-Rustempasic Christina Conrardy Suxiang Tong Ivan V. Kuzmin Bernard Agwanda Robert F. Breiman Krisztian Banyai Michael Niezgoda Charles E. Rupprecht Jon R. Gentsch Michael D. Bowen |
| author_facet | Mathew D. Esona Slavica Mijatovic-Rustempasic Christina Conrardy Suxiang Tong Ivan V. Kuzmin Bernard Agwanda Robert F. Breiman Krisztian Banyai Michael Niezgoda Charles E. Rupprecht Jon R. Gentsch Michael D. Bowen |
| author_sort | Mathew D. Esona |
| collection | DOAJ |
| description | Bats are known reservoirs of viral zoonoses. We report genetic characterization of a bat rotavirus (Bat/KE4852/07) detected in the feces of a straw-colored fruit bat (Eidolon helvum). Six bat rotavirus genes (viral protein [VP] 2, VP6, VP7, nonstructural protein [NSP] 2, NSP3, and NSP5) shared ancestry with other mammalian rotaviruses but were distantly related. The VP4 gene was nearly identical to that of human P[6] rotavirus strains, and the NSP4 gene was closely related to those of previously described mammalian rotaviruses, including human strains. Analysis of partial sequence of the VP1 gene indicated that it was distinct from cognate genes of other rotaviruses. No sequences were obtained for the VP3 and NSP1 genes of the bat rotavirus. This rotavirus was designated G25-P[6]-I15-R8(provisional)-C8-Mx-Ax-N8-T11-E2-H10. Results suggest that several reassortment events have occurred between human, animal, and bat rotaviruses. Several additional rotavirus strains were detected in bats. |
| first_indexed | 2024-12-11T19:29:05Z |
| format | Article |
| id | doaj.art-cd2d2ec2923f4da4b5072f54ce27284a |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-11T19:29:05Z |
| publishDate | 2010-12-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-cd2d2ec2923f4da4b5072f54ce27284a2022-12-22T00:53:20ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592010-12-0116121844185210.3201/eid1612.101089Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum)Mathew D. EsonaSlavica Mijatovic-RustempasicChristina ConrardySuxiang TongIvan V. KuzminBernard AgwandaRobert F. BreimanKrisztian BanyaiMichael NiezgodaCharles E. RupprechtJon R. GentschMichael D. BowenBats are known reservoirs of viral zoonoses. We report genetic characterization of a bat rotavirus (Bat/KE4852/07) detected in the feces of a straw-colored fruit bat (Eidolon helvum). Six bat rotavirus genes (viral protein [VP] 2, VP6, VP7, nonstructural protein [NSP] 2, NSP3, and NSP5) shared ancestry with other mammalian rotaviruses but were distantly related. The VP4 gene was nearly identical to that of human P[6] rotavirus strains, and the NSP4 gene was closely related to those of previously described mammalian rotaviruses, including human strains. Analysis of partial sequence of the VP1 gene indicated that it was distinct from cognate genes of other rotaviruses. No sequences were obtained for the VP3 and NSP1 genes of the bat rotavirus. This rotavirus was designated G25-P[6]-I15-R8(provisional)-C8-Mx-Ax-N8-T11-E2-H10. Results suggest that several reassortment events have occurred between human, animal, and bat rotaviruses. Several additional rotavirus strains were detected in bats.https://wwwnc.cdc.gov/eid/article/16/12/10-1089_articleStraw-colored fruit batEidolon helvumrotavirusvirusesreassortmentheterologous genome segments |
| spellingShingle | Mathew D. Esona Slavica Mijatovic-Rustempasic Christina Conrardy Suxiang Tong Ivan V. Kuzmin Bernard Agwanda Robert F. Breiman Krisztian Banyai Michael Niezgoda Charles E. Rupprecht Jon R. Gentsch Michael D. Bowen Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum) Emerging Infectious Diseases Straw-colored fruit bat Eidolon helvum rotavirus viruses reassortment heterologous genome segments |
| title | Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum) |
| title_full | Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum) |
| title_fullStr | Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum) |
| title_full_unstemmed | Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum) |
| title_short | Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum) |
| title_sort | reassortant group a rotavirus from straw colored fruit bat eidolon helvum |
| topic | Straw-colored fruit bat Eidolon helvum rotavirus viruses reassortment heterologous genome segments |
| url | https://wwwnc.cdc.gov/eid/article/16/12/10-1089_article |
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