Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepatica
The presence and distribution of surface carbohydrates in the tissues of Galba truncatula snails uninfected or after infection with Fasciola hepatica as well as on the surface of the snail-pathogenic larval stages of the parasite were studied by lectin labelling assay. This is an attempt to find sim...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2016-01-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016005001408&lng=en&tlng=en |
| _version_ | 1797704821596225536 |
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| author | Katya Georgieva Liliya Georgieva Yana Mizinska-Boevska Stoyanka R Stoitsova |
| author_facet | Katya Georgieva Liliya Georgieva Yana Mizinska-Boevska Stoyanka R Stoitsova |
| author_sort | Katya Georgieva |
| collection | DOAJ |
| description | The presence and distribution of surface carbohydrates in the tissues of Galba truncatula snails uninfected or after infection with Fasciola hepatica as well as on the surface of the snail-pathogenic larval stages of the parasite were studied by lectin labelling assay. This is an attempt to find similarities that indicate possible mimicry, utilised by the parasite as an evasion strategy in this snail-trematode system. Different binding patterns were identified on head-foot-mantle, hepatopancreas, genital glands, renopericardial complex of the host as well as of the snail-pathogenic larval stages of F. hepatica. The infection with F. hepatica leads to changes of labelling with Glycine max in the head-mantle cells and Arachis hypogaea in the tubular epithelium of the hepatopancreas. The lectin binding on the other snail tissues is not changed by the development of the larvae. Our data clearly demonstrated the similarity in labelling of G. truncatula tissues and the surface of the snail-pathogenic larval stages of F. hepatica. The role of glycosylation of the contact surfaces of both organisms in relation to the host-parasite interactions is also discussed. |
| first_indexed | 2024-03-12T05:26:10Z |
| format | Article |
| id | doaj.art-cd2e48bdb72f4add8ade8bf87e16faab |
| institution | Directory Open Access Journal |
| issn | 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T05:26:10Z |
| publishDate | 2016-01-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-cd2e48bdb72f4add8ade8bf87e16faab2023-09-03T07:24:28ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz1678-80602016-01-01010.1590/0074-02760160141S0074-02762016005001408Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepaticaKatya GeorgievaLiliya GeorgievaYana Mizinska-BoevskaStoyanka R StoitsovaThe presence and distribution of surface carbohydrates in the tissues of Galba truncatula snails uninfected or after infection with Fasciola hepatica as well as on the surface of the snail-pathogenic larval stages of the parasite were studied by lectin labelling assay. This is an attempt to find similarities that indicate possible mimicry, utilised by the parasite as an evasion strategy in this snail-trematode system. Different binding patterns were identified on head-foot-mantle, hepatopancreas, genital glands, renopericardial complex of the host as well as of the snail-pathogenic larval stages of F. hepatica. The infection with F. hepatica leads to changes of labelling with Glycine max in the head-mantle cells and Arachis hypogaea in the tubular epithelium of the hepatopancreas. The lectin binding on the other snail tissues is not changed by the development of the larvae. Our data clearly demonstrated the similarity in labelling of G. truncatula tissues and the surface of the snail-pathogenic larval stages of F. hepatica. The role of glycosylation of the contact surfaces of both organisms in relation to the host-parasite interactions is also discussed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016005001408&lng=en&tlng=enGalba truncatulaFasciola hepaticasurface carbohydrateslectin labellingcarbohydrate similarity |
| spellingShingle | Katya Georgieva Liliya Georgieva Yana Mizinska-Boevska Stoyanka R Stoitsova Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepatica Memorias do Instituto Oswaldo Cruz Galba truncatula Fasciola hepatica surface carbohydrates lectin labelling carbohydrate similarity |
| title | Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepatica |
| title_full | Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepatica |
| title_fullStr | Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepatica |
| title_full_unstemmed | Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepatica |
| title_short | Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepatica |
| title_sort | study of surface carbohydrates in galba truncatula tissues before and after infection with fasciola hepatica |
| topic | Galba truncatula Fasciola hepatica surface carbohydrates lectin labelling carbohydrate similarity |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016005001408&lng=en&tlng=en |
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