Efficacy of puerarin in rats with focal cerebral ischemia through modulation of the SIRT1/HIF-1α/VEGF signaling pathway and its effect on synaptic plasticity

Efficacy of puerarin in rats with focal cerebral ischemia through modulation of the SIRT1/HIF-1α/VEGF signaling pathway and its effect on synaptic plasticity

This study aimed to evaluate the efficacy of puerarin and its effect on synaptic plasticity in rats with focal cerebral ischemia (FCI) by modulating the silent mating type information regulation 2 homolog (SIRT1)/hypoxia-inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) signalin...

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Bibliographic Details
Main Authors: Xin Liu, Xiwen Sui, Yuqin Zhang, Rongchao Yue, Shifu Yin
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Heliyon
Subjects:
Focal cerebral ischemia
Puerarin
SIRT1/HIF-1α/VEGF signaling Pathway
Synaptic plasticity
Signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023030797

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http://www.sciencedirect.com/science/article/pii/S2405844023030797

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