Fine-scale Identification of the Most Likely Source of a Human Plague Infection

Fine-scale Identification of the Most Likely Source of a Human Plague Infection

We describe an analytic approach to provide fine-scale discrimination among multiple infection source hypotheses. This approach uses mutation-rate data for rapidly evolving multiple locus variable-number tandem repeat loci in probabilistic models to identify the most likely source. We illustrate the...

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Bibliographic Details
Main Authors: Rebecca E. Colman, Amy J. Vogler, Jennifer L. Lowell, Kenneth L. Gage, Christina Morway, Pamela J. Reynolds, Paul Ettestad, Paul Keim, Michael Y. Kosoy, David M. Wagner
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2009-10-01
Series:Emerging Infectious Diseases
Subjects:
Molecular epidemiology
plague
Yersinia pestis
VNTR
MLVA
probabilistic modeling
Online Access:https://wwwnc.cdc.gov/eid/article/15/10/09-0188_article

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