CCND3 is indispensable for the maintenance of B-cell acute lymphoblastic leukemia
Abstract The D-type cyclins (CCND1, CCND2, and CCND3) in association with CDK4/6 are known drivers of cell cycle progression. We reported previously that inactivation of FOXO1 confers growth arrest and apoptosis in B-ALL, partially mediated by subsequent depletion of CCND3. Given that previously the...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2022-01-01
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| Series: | Oncogenesis |
| Online Access: | https://doi.org/10.1038/s41389-021-00377-0 |