Expression and Correlation of Complement C3 and C4 in Serum and Maternal-Fetal Interface in Patients with Unexplained Recurrent Spontaneous Abortion: A Prospective Cohort Study

Expression and Correlation of Complement C3 and C4 in Serum and Maternal-Fetal Interface in Patients with Unexplained Recurrent Spontaneous Abortion: A Prospective Cohort Study

Background: In this study, we sought to detect the expression of complement C3 and C4 in serum and maternal-fetal interface in patients with unexplained recurrent spontaneous abortion, and analyze their correlation, in order to explore the clinical significance and role of C3 and C4 in unexplained r...

Full description

Bibliographic Details
Main Authors:	Zhengxin Zhou, Huixia Xie, Miao Liu, Ruopeng Li, Wenjing Jiang, Yan Zheng, Qun Lv
Format:	Article
Language:	English
Published:	IMR Press 2023-11-01
Series:	Clinical and Experimental Obstetrics & Gynecology
Subjects:	unexplained recurrent spontaneous abortion maternal-fetal immune tolerance balance complement c3 complement c4
Online Access:	https://www.imrpress.com/journal/CEOG/50/11/10.31083/j.ceog5011252

Similar Items

Association of emerging and legacy per- and polyfluoroalkyl substances with unexplained recurrent spontaneous abortion
by: Min Nian, et al.
Published: (2022-07-01)

A missense variant in NCF1 is associated with susceptibility to unexplained recurrent spontaneous abortion
by: Du Mengxuan, et al.
Published: (2022-11-01)

Research progress of immune balance and genetic polymorphism in unexplained recurrent abortion
by: Yafei Kang, et al.
Published: (2023-10-01)

Polarization disorder of decidual NK cells in unexplained recurrent spontaneous abortion revealed by single-cell transcriptome analysis
by: Dingchen Pan, et al.
Published: (2022-07-01)

Temporal changes in cyclinD-CDK4/CDK6 and cyclinE-CDK2 pathways: implications for the mechanism of deficient decidualization in an immune-based mouse model of unexplained recurrent spontaneous abortion
by: Zhuo Chang, et al.
Published: (2022-09-01)

Complement C7 and clusterin form a complex in circulation
by: Mariam Massri, et al.
Published: (2024-01-01)

Complement C4, C4A and C4a – What they do and how they differ
by: Meike Heurich, et al.
Published: (2024-08-01)

Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases
by: Katherine eLintner, et al.
Published: (2016-02-01)

The Evaluation of the Level of C3 and C4 Complements in Unstimulated Saliva of Patients with Oral Lichen Planus
by: Bita Rohani, et al.
Published: (2020-06-01)

M1 macrophages decrease in the deciduae from normal pregnancies but not from spontaneous abortions or unexplained recurrent spontaneous abortions
by: Fang-Yu Tsao, et al.
Published: (2018-03-01)

Effect of IVIG therapy on pregnant women with unexplained recurrent spontaneous abortion: a systematic review and meta-analysis
by: Qiao Ling, et al.
Published: (2024-08-01)

Elevated Homocysteine Levels and Endothelial Dysfunction in Unexplained Recurrent Spontaneous Abortion
by: Qi L, et al.
Published: (2025-02-01)

Clinical effect of lymphocyte immunotherapy on patients with unexplained recurrent spontaneous abortion
by: Sudong Liu, et al.
Published: (2021-12-01)

Compromised C3b-VSIG4 axis between decidual NK cells and macrophages contributes to recurrent spontaneous abortion
by: Siao Chen, et al.
Published: (2024-11-01)

circRNA-DURSA regulates trophoblast apoptosis via miR-760-HIST1H2BE axis in unexplained recurrent spontaneous abortion
by: Minyue Tang, et al.
Published: (2021-12-01)

Lipid imbalance and inflammatory oxylipin cascade at the maternal-fetal interface in recurrent spontaneous abortion
by: Hao Liu, et al.
Published: (2024-12-01)

Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein
by: Aleksandra Urban, et al.
Published: (2021-11-01)

Effects of sera taken from women with recurrent spontaneous abortion on sperm motility and apoptosis
by: Tahereh Talaei-khozani, et al.
Published: (2011-01-01)

Structure-Based Modeling of Complement C4 Mediated Neutralization of Adenovirus
by: Corey C. Emerson, et al.
Published: (2021-01-01)

Influence of methylenetetrahydrofolate reductase gene polymorphism C677T on the risk of recurrent spontaneous abortions
by: Svirčev Miloš, et al.
Published: (2018-01-01)

Diagnosis of spontaneous bacterial peritonitis
by: Naglaa A El-Gendy, et al.
Published: (2014-01-01)

Structural Model for Factor X Inhibition of IgM and Complement-Mediated Neutralization of Adenovirus
by: Nicole Wagner, et al.
Published: (2023-06-01)

Low-dose aspirin protects unexplained recurrent spontaneous abortion via downregulation of HMGB1 inflammation activation
by: Xiaofeng Xu, et al.
Published: (2022-11-01)

Intercellular communication involving macrophages at the maternal-fetal interface may be a pivotal mechanism of URSA: a novel discovery from transcriptomic data
by: Xiaoxuan Zhao, et al.
Published: (2023-05-01)

Association between urinary polycyclic aromatic hydrocarbons and unexplained recurrent spontaneous abortion from a case-control study
by: Chunxian Lv, et al.
Published: (2024-03-01)

Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy
by: Limei Zhao, et al.
Published: (2017-05-01)

AMPK-mTOR pathway modulates glycolysis reprogramming in unexplained recurrent spontaneous abortion
by: Yihong Chen, et al.
Published: (2024-12-01)

KLF4 regulates trophoblast function and associates with unexplained recurrent spontaneous abortion
by: Yiling Tan, et al.
Published: (2024-10-01)

Complement C3 inhibitor in patients with paroxysmal nocturnal hemoglobinuria with suboptimal response to C5 inhibitor therapy
by: M. V. Marchenko, et al.
Published: (2024-09-01)

SERUM C3 AND SERUM C4 COMPLEMENT IN PATIENTS WITH BURN TRAUMA AND CORRELATION WITH BURN INJURY SEVERITY
by: Arslanagic Selma, et al.
Published: (2022-07-01)

Complement C1q Enhances Primary Hemostasis
by: Claudia Donat, et al.
Published: (2020-07-01)

Mediating effect of oxidative stress on association between nicotine and unexplained recurrent spontaneous abortion
by: Dandan LI, et al.
Published: (2022-05-01)

Prediction of Unexplained Recurrent Miscarriages Using Thromboelastography
by: Xu J, et al.
Published: (2024-09-01)

Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-Level in Plasma Samples From Mice and Humans
by: Lene Halkjær, et al.
Published: (2020-05-01)

Association of thyroid peroxidase antibodies with the rate of first-trimester miscarriage in euthyroid women with unexplained recurrent spontaneous abortion
by: Meilan Liu, et al.
Published: (2022-08-01)

Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity
by: D. V. A. Khoa, et al.
Published: (2015-09-01)

Association between serum complements and kidney function in patients with diabetic kidney disease
by: Meng-chao Liu, et al.
Published: (2023-11-01)

Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?
by: Marco Mannes, et al.
Published: (2023-03-01)

Determination the Level of Complement Protein C3 and C4 in Gastric Ulcers Patients in Baqubah City, Iraq
by: Maha Falh Nazzal, et al.
Published: (2018-08-01)

Determination the Level of Complement Protein C3 and C4 in Gastric Ulcers Patients in Baqubah City, Iraq
by: Maha Falh Nazzal, et al.
Published: (2018-08-01)