Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The basement membrane is located at tissue interfaces, but how it mediates distinct inter-tissue interactions is unclear. Here, the authors systematically define the spatial heterogeneity of skin basement membrane composition and show its functional importance in inter-tissue interactions.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2021-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-22881-y |
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author | Ko Tsutsui Hiroki Machida Asako Nakagawa Kyungmin Ahn Ritsuko Morita Kiyotoshi Sekiguchi Jeffrey H. Miner Hironobu Fujiwara |
author_facet | Ko Tsutsui Hiroki Machida Asako Nakagawa Kyungmin Ahn Ritsuko Morita Kiyotoshi Sekiguchi Jeffrey H. Miner Hironobu Fujiwara |
author_sort | Ko Tsutsui |
collection | DOAJ |
description | The basement membrane is located at tissue interfaces, but how it mediates distinct inter-tissue interactions is unclear. Here, the authors systematically define the spatial heterogeneity of skin basement membrane composition and show its functional importance in inter-tissue interactions. |
first_indexed | 2024-12-13T16:10:46Z |
format | Article |
id | doaj.art-cd420d1bdef94731b034f9f7e801a566 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-13T16:10:46Z |
publishDate | 2021-05-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-cd420d1bdef94731b034f9f7e801a5662022-12-21T23:38:57ZengNature PortfolioNature Communications2041-17232021-05-0112111810.1038/s41467-021-22881-yMapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactionsKo Tsutsui0Hiroki Machida1Asako Nakagawa2Kyungmin Ahn3Ritsuko Morita4Kiyotoshi Sekiguchi5Jeffrey H. Miner6Hironobu Fujiwara7Laboratory for Tissue Microenvironment, RIKEN Center for Biosystems Dynamics Research (BDR)Laboratory for Tissue Microenvironment, RIKEN Center for Biosystems Dynamics Research (BDR)Laboratory for Tissue Microenvironment, RIKEN Center for Biosystems Dynamics Research (BDR)Laboratory for Tissue Microenvironment, RIKEN Center for Biosystems Dynamics Research (BDR)Laboratory for Tissue Microenvironment, RIKEN Center for Biosystems Dynamics Research (BDR)Laboratory of Matrixome Research and Application, Institute for Protein Research, Osaka UniversityDivision of Nephrology, Department of Medicine, Washington University School of MedicineLaboratory for Tissue Microenvironment, RIKEN Center for Biosystems Dynamics Research (BDR)The basement membrane is located at tissue interfaces, but how it mediates distinct inter-tissue interactions is unclear. Here, the authors systematically define the spatial heterogeneity of skin basement membrane composition and show its functional importance in inter-tissue interactions.https://doi.org/10.1038/s41467-021-22881-y |
spellingShingle | Ko Tsutsui Hiroki Machida Asako Nakagawa Kyungmin Ahn Ritsuko Morita Kiyotoshi Sekiguchi Jeffrey H. Miner Hironobu Fujiwara Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions Nature Communications |
title | Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions |
title_full | Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions |
title_fullStr | Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions |
title_full_unstemmed | Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions |
title_short | Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions |
title_sort | mapping the molecular and structural specialization of the skin basement membrane for inter tissue interactions |
url | https://doi.org/10.1038/s41467-021-22881-y |
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