Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis

Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis

Abstract Allelic variants of genes encoding for the Fc gamma receptors IIIA and IIA have been associated with the clinical response to cell‐depleting antibodies in lymphoma patients. Here, we tested the hypothesis that FCGR3A and FCGR2A high‐affinity polymorphisms predict clinical outcomes to alemtu...

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Bibliographic Details
Main Authors: Christian W. Keller, Tobias Ruck, Donal McHugh, Steffen Pfeuffer, Catharina C. Gross, Catharina Korsukewitz, Nico Melzer, Luisa Klotz, Sven G. Meuth, Christian Münz, Falk Nimmerjahn, Heinz Wiendl, Jan D. Lünemann
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.50935

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