A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple

Prurigo pigmentosa (PP) is probably underdiagnosed due to lack of awareness. Previously, it was assumed that PP primarily affected Japanese females; however, more cases are reported worldwide, and the pathogenesis is still not completely understood. In this case report, we present two healthy Danish...

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Main Authors: Maria Danielsen, Kristine Pallesen, Rikke Riber-Hansen, Anne Bregnhøj
Format: Article
Language:English
Published: Karger Publishers 2023-01-01
Series:Case Reports in Dermatology
Subjects:
Online Access:https://www.karger.com/Article/FullText/528422
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author Maria Danielsen
Kristine Pallesen
Rikke Riber-Hansen
Anne Bregnhøj
author_facet Maria Danielsen
Kristine Pallesen
Rikke Riber-Hansen
Anne Bregnhøj
author_sort Maria Danielsen
collection DOAJ
description Prurigo pigmentosa (PP) is probably underdiagnosed due to lack of awareness. Previously, it was assumed that PP primarily affected Japanese females; however, more cases are reported worldwide, and the pathogenesis is still not completely understood. In this case report, we present two healthy Danish siblings, who developed PP approximately 2 weeks after starting a ketogenic diet, suggesting that both increased levels of ketone bodies in the blood together with a genetic predisposition might play a role in the development of PP.
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spelling doaj.art-cd44d79f81754536b7e102c2877333a62023-02-23T11:31:01ZengKarger PublishersCase Reports in Dermatology1662-65672023-01-01151263010.1159/000528422528422A Rare Case of Prurigo Pigmentosa in a Danish Sibling CoupleMaria Danielsen0Kristine Pallesen1Rikke Riber-Hansen2Anne Bregnhøj3Department of Dermatology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Dermatology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Pathology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Dermatology, Aarhus University Hospital, Aarhus, DenmarkPrurigo pigmentosa (PP) is probably underdiagnosed due to lack of awareness. Previously, it was assumed that PP primarily affected Japanese females; however, more cases are reported worldwide, and the pathogenesis is still not completely understood. In this case report, we present two healthy Danish siblings, who developed PP approximately 2 weeks after starting a ketogenic diet, suggesting that both increased levels of ketone bodies in the blood together with a genetic predisposition might play a role in the development of PP.https://www.karger.com/Article/FullText/528422case reportprurigo pigmentosaketogenic dietsiblingspruritus
spellingShingle Maria Danielsen
Kristine Pallesen
Rikke Riber-Hansen
Anne Bregnhøj
A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple
Case Reports in Dermatology
case report
prurigo pigmentosa
ketogenic diet
siblings
pruritus
title A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple
title_full A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple
title_fullStr A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple
title_full_unstemmed A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple
title_short A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple
title_sort rare case of prurigo pigmentosa in a danish sibling couple
topic case report
prurigo pigmentosa
ketogenic diet
siblings
pruritus
url https://www.karger.com/Article/FullText/528422
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