Phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatite
Calcium phosphate coatings containing brushite, calcite, and apatite were obtained by electrochemical deposition on titanium plates at room temperature, pH 5, constant current density 30 mA/cm2, from CaCO3/Ca(H2PO4)2 suspension electrolyte. A layer of amorphous apatite was deposited by the biomimeti...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Tver State University
2023-12-01
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| Series: | Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов |
| Subjects: | |
| Online Access: | https://physchemaspects.ru/2023/doi-10-26456-pcascnn-2023-15-708/?lang=en |
| _version_ | 1797408465410326528 |
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| author | A.E. Doroshenko V.K. Krut’ko O.N. Musskaya A.I. Dovnar O.B. Ostrovskaya E.M. Doroshenko A.I. Kulak |
| author_facet | A.E. Doroshenko V.K. Krut’ko O.N. Musskaya A.I. Dovnar O.B. Ostrovskaya E.M. Doroshenko A.I. Kulak |
| author_sort | A.E. Doroshenko |
| collection | DOAJ |
| description | Calcium phosphate coatings containing brushite, calcite, and apatite were obtained by electrochemical deposition on titanium plates at room temperature, pH 5, constant current density 30 mA/cm2, from CaCO3/Ca(H2PO4)2 suspension electrolyte. A layer of amorphous apatite was deposited by the biomimetic method, by keeping the coatings in a concentrated modeling solution of Simulated Body Fluid. As a result of heat treatment at 800°C, apatite crystallized into hydroxyapatite, calcite decomposed to calcium oxide, and titanium was covered with a layer of titanium (IV) oxide. Preclinical studies on rats in vivo for 3 months showed increased osseointegration of plates with calcium phosphate coatings compared to uncoated titanium. Titanium implants with calcium phosphate coatings enriched with hydroxyapatite are promising for use in neurosurgery, dentistry, orthopedics due to the absence of inflammatory reactions from the body and increased osseointegration. |
| first_indexed | 2024-03-09T03:58:52Z |
| format | Article |
| id | doaj.art-cd45375313154878811f90134631806d |
| institution | Directory Open Access Journal |
| issn | 2226-4442 2658-4360 |
| language | Russian |
| last_indexed | 2024-03-09T03:58:52Z |
| publishDate | 2023-12-01 |
| publisher | Tver State University |
| record_format | Article |
| series | Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов |
| spelling | doaj.art-cd45375313154878811f90134631806d2023-12-03T14:16:51ZrusTver State UniversityФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов2226-44422658-43602023-12-011570871710.26456/pcascnn/2023.15.708Phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatiteA.E. Doroshenko0V.K. Krut’ko1O.N. Musskaya2A.I. Dovnar3O.B. Ostrovskaya4E.M. Doroshenko5A.I. Kulak6Institute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus, Minsk, Republic of BelarusInstitute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus, Minsk, Republic of BelarusInstitute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus, Minsk, Republic of BelarusGrodno State Medical University, Grodno, Republic of BelarusGrodno State Medical University, Grodno, Republic of BelarusGrodno State Medical University, Grodno, Republic of BelarusInstitute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus, Minsk, Republic of BelarusCalcium phosphate coatings containing brushite, calcite, and apatite were obtained by electrochemical deposition on titanium plates at room temperature, pH 5, constant current density 30 mA/cm2, from CaCO3/Ca(H2PO4)2 suspension electrolyte. A layer of amorphous apatite was deposited by the biomimetic method, by keeping the coatings in a concentrated modeling solution of Simulated Body Fluid. As a result of heat treatment at 800°C, apatite crystallized into hydroxyapatite, calcite decomposed to calcium oxide, and titanium was covered with a layer of titanium (IV) oxide. Preclinical studies on rats in vivo for 3 months showed increased osseointegration of plates with calcium phosphate coatings compared to uncoated titanium. Titanium implants with calcium phosphate coatings enriched with hydroxyapatite are promising for use in neurosurgery, dentistry, orthopedics due to the absence of inflammatory reactions from the body and increased osseointegration.https://physchemaspects.ru/2023/doi-10-26456-pcascnn-2023-15-708/?lang=encalcium phosphate coatingsbrushitecalcitesbf model solutionapatitehydroxyapatite |
| spellingShingle | A.E. Doroshenko V.K. Krut’ko O.N. Musskaya A.I. Dovnar O.B. Ostrovskaya E.M. Doroshenko A.I. Kulak Phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatite Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов calcium phosphate coatings brushite calcite sbf model solution apatite hydroxyapatite |
| title | Phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatite |
| title_full | Phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatite |
| title_fullStr | Phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatite |
| title_full_unstemmed | Phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatite |
| title_short | Phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatite |
| title_sort | phase composition and biocompatibility of calcium phosphate coatings on titanium enriched with hydroxyapatite |
| topic | calcium phosphate coatings brushite calcite sbf model solution apatite hydroxyapatite |
| url | https://physchemaspects.ru/2023/doi-10-26456-pcascnn-2023-15-708/?lang=en |
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