Metabolic effects of an entero-omentectomy in mildly obese type 2 diabetes mellitus patients after three years
BACKGROUND: Various digestive tract procedures effectively improve metabolic syndrome, especially the control of type 2 diabetes mellitus. Very good metabolic results have been shown with vertical gastrectomy and entero-omentectomy; however, the metabolic effects of an isolated entero-omentectomy ha...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier España
2011-01-01
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| Series: | Clinics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000700018 |
| _version_ | 1811223758306803712 |
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| author | Fábio Quirilo Milleo Antonio Carlos Ligocki Campos Sérgio Santoro Arnaldo Lacombe Marco Aurélio Santo Marcelo Ricardo Vicari Viviane Nogaroto Roberto Ferreira Artoni |
| author_facet | Fábio Quirilo Milleo Antonio Carlos Ligocki Campos Sérgio Santoro Arnaldo Lacombe Marco Aurélio Santo Marcelo Ricardo Vicari Viviane Nogaroto Roberto Ferreira Artoni |
| author_sort | Fábio Quirilo Milleo |
| collection | DOAJ |
| description | BACKGROUND: Various digestive tract procedures effectively improve metabolic syndrome, especially the control of type 2 diabetes mellitus. Very good metabolic results have been shown with vertical gastrectomy and entero-omentectomy; however, the metabolic effects of an isolated entero-omentectomy have not been previously studied. METHODS: Nine patients with type 2 diabetes mellitus and a body mass index ranging from 29 to 34.8 kg/m² underwent an entero-omentectomy procedure that consisted of an enterectomy of the middle jejunum and exeresis of the major part of the omentum performed through a mini-laparotomy. Glucagon-like peptide-1 and peptide YY were measured preoperatively and three months following the operation. Fasting and postprandial variations in glycemia, insulinemia, triglyceridemia, hemoglobin A1c, and body mass index were determined in the preoperative period and 3, 18 and, 36 months after the operation. RESULTS: All patients significantly improved the control of their type 2 diabetes mellitus. Postprandial secretion of peptide YY and Glucagon-like peptide-1 were enhanced, whereas hemoglobin A1c, fasting and postprandial glucose, insulin, and triglyceride levels were significantly reduced. Mean body mass index was reduced from 31.1 to 27.3 kg/m². No major surgical or nutritional complications occurred. CONCLUSIONS: Entero-omentectomy is easy and safe to perform. A simple reduction in jejunal extension and visceral fat causes important improvements in the metabolic profile. |
| first_indexed | 2024-04-12T08:37:54Z |
| format | Article |
| id | doaj.art-cd48d41e0616486abd944f92c90e7ffb |
| institution | Directory Open Access Journal |
| issn | 1807-5932 1980-5322 |
| language | English |
| last_indexed | 2024-04-12T08:37:54Z |
| publishDate | 2011-01-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-cd48d41e0616486abd944f92c90e7ffb2022-12-22T03:39:58ZengElsevier EspañaClinics1807-59321980-53222011-01-016671227123310.1590/S1807-59322011000700018Metabolic effects of an entero-omentectomy in mildly obese type 2 diabetes mellitus patients after three yearsFábio Quirilo MilleoAntonio Carlos Ligocki CamposSérgio SantoroArnaldo LacombeMarco Aurélio SantoMarcelo Ricardo VicariViviane NogarotoRoberto Ferreira ArtoniBACKGROUND: Various digestive tract procedures effectively improve metabolic syndrome, especially the control of type 2 diabetes mellitus. Very good metabolic results have been shown with vertical gastrectomy and entero-omentectomy; however, the metabolic effects of an isolated entero-omentectomy have not been previously studied. METHODS: Nine patients with type 2 diabetes mellitus and a body mass index ranging from 29 to 34.8 kg/m² underwent an entero-omentectomy procedure that consisted of an enterectomy of the middle jejunum and exeresis of the major part of the omentum performed through a mini-laparotomy. Glucagon-like peptide-1 and peptide YY were measured preoperatively and three months following the operation. Fasting and postprandial variations in glycemia, insulinemia, triglyceridemia, hemoglobin A1c, and body mass index were determined in the preoperative period and 3, 18 and, 36 months after the operation. RESULTS: All patients significantly improved the control of their type 2 diabetes mellitus. Postprandial secretion of peptide YY and Glucagon-like peptide-1 were enhanced, whereas hemoglobin A1c, fasting and postprandial glucose, insulin, and triglyceride levels were significantly reduced. Mean body mass index was reduced from 31.1 to 27.3 kg/m². No major surgical or nutritional complications occurred. CONCLUSIONS: Entero-omentectomy is easy and safe to perform. A simple reduction in jejunal extension and visceral fat causes important improvements in the metabolic profile.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000700018Type 2 diabetes mellitusGLP-1PYYEnterectomyOmentectomyMetabolic surgery |
| spellingShingle | Fábio Quirilo Milleo Antonio Carlos Ligocki Campos Sérgio Santoro Arnaldo Lacombe Marco Aurélio Santo Marcelo Ricardo Vicari Viviane Nogaroto Roberto Ferreira Artoni Metabolic effects of an entero-omentectomy in mildly obese type 2 diabetes mellitus patients after three years Clinics Type 2 diabetes mellitus GLP-1 PYY Enterectomy Omentectomy Metabolic surgery |
| title | Metabolic effects of an entero-omentectomy in mildly obese type 2 diabetes mellitus patients after three years |
| title_full | Metabolic effects of an entero-omentectomy in mildly obese type 2 diabetes mellitus patients after three years |
| title_fullStr | Metabolic effects of an entero-omentectomy in mildly obese type 2 diabetes mellitus patients after three years |
| title_full_unstemmed | Metabolic effects of an entero-omentectomy in mildly obese type 2 diabetes mellitus patients after three years |
| title_short | Metabolic effects of an entero-omentectomy in mildly obese type 2 diabetes mellitus patients after three years |
| title_sort | metabolic effects of an entero omentectomy in mildly obese type 2 diabetes mellitus patients after three years |
| topic | Type 2 diabetes mellitus GLP-1 PYY Enterectomy Omentectomy Metabolic surgery |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000700018 |
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