Hydroxypropyl-β-Cyclodextrin as a Green Co-Solvent in the Aqueous Extraction of Polyphenols from Waste Orange Peels
There is, to-date, an expanding interest concerning the use of cyclodextrins as green food-grade co-solvents in the aqueous extraction of polyphenols, however, data regarding polyphenol extraction from waste orange peels (WOP) are lacking. On this ground, hydroxypropyl β-cyclodextrin (HP-β-CD), a hi...
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MDPI AG
2020-08-01
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| Series: | Beverages |
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| Online Access: | https://www.mdpi.com/2306-5710/6/3/50 |
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| author | Achillia Lakka Stavros Lalas Dimitris P. Makris |
| author_facet | Achillia Lakka Stavros Lalas Dimitris P. Makris |
| author_sort | Achillia Lakka |
| collection | DOAJ |
| description | There is, to-date, an expanding interest concerning the use of cyclodextrins as green food-grade co-solvents in the aqueous extraction of polyphenols, however, data regarding polyphenol extraction from waste orange peels (WOP) are lacking. On this ground, hydroxypropyl β-cyclodextrin (HP-β-CD), a highly water-soluble cyclodextrin, was used to develop a simple and straightforward methodology for the effective recovery of WOP polyphenols. Process optimization by response surface showed that maximum total polyphenol recovery (26.30 ± 1.49 mg gallic acid equivalents g<sup>−1</sup> dry mass) could be accomplished with 15 mM HP-β-CD at 40 °C. On the other hand, integration of ultrasonication pretreatment was found unsuitable, as it resulted in reduced polyphenol yield. Examination of solvent acidity indicated that polyphenol extraction may be enhanced at pH 4, but the difference was non-significant (<i>p</i> > 0.05) compared to yields attained at pH 2, 3, and 5. Extraction of WOP polyphenols with HP-β-CD was shown to provide significantly higher hesperidin yield compared to 60% (<i>v</i>/<i>v</i>) aqueous ethanol, which suggested selectivity of HP-β-CD toward this polyphenolic metabolite. |
| first_indexed | 2024-03-10T17:43:10Z |
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| id | doaj.art-cd48f4a1d06d4242bb2d5bf161355c30 |
| institution | Directory Open Access Journal |
| issn | 2306-5710 |
| language | English |
| last_indexed | 2024-03-10T17:43:10Z |
| publishDate | 2020-08-01 |
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| record_format | Article |
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| spelling | doaj.art-cd48f4a1d06d4242bb2d5bf161355c302023-11-20T09:37:53ZengMDPI AGBeverages2306-57102020-08-01635010.3390/beverages6030050Hydroxypropyl-β-Cyclodextrin as a Green Co-Solvent in the Aqueous Extraction of Polyphenols from Waste Orange PeelsAchillia Lakka0Stavros Lalas1Dimitris P. Makris2Green Processes & Biorefinery Group, Department of Food Science & Nutrition, School of Agricultural Sciences, University of Thessaly, N. Temponera Str., 43100 Karditsa, GreeceGreen Processes & Biorefinery Group, Department of Food Science & Nutrition, School of Agricultural Sciences, University of Thessaly, N. Temponera Str., 43100 Karditsa, GreeceGreen Processes & Biorefinery Group, Department of Food Science & Nutrition, School of Agricultural Sciences, University of Thessaly, N. Temponera Str., 43100 Karditsa, GreeceThere is, to-date, an expanding interest concerning the use of cyclodextrins as green food-grade co-solvents in the aqueous extraction of polyphenols, however, data regarding polyphenol extraction from waste orange peels (WOP) are lacking. On this ground, hydroxypropyl β-cyclodextrin (HP-β-CD), a highly water-soluble cyclodextrin, was used to develop a simple and straightforward methodology for the effective recovery of WOP polyphenols. Process optimization by response surface showed that maximum total polyphenol recovery (26.30 ± 1.49 mg gallic acid equivalents g<sup>−1</sup> dry mass) could be accomplished with 15 mM HP-β-CD at 40 °C. On the other hand, integration of ultrasonication pretreatment was found unsuitable, as it resulted in reduced polyphenol yield. Examination of solvent acidity indicated that polyphenol extraction may be enhanced at pH 4, but the difference was non-significant (<i>p</i> > 0.05) compared to yields attained at pH 2, 3, and 5. Extraction of WOP polyphenols with HP-β-CD was shown to provide significantly higher hesperidin yield compared to 60% (<i>v</i>/<i>v</i>) aqueous ethanol, which suggested selectivity of HP-β-CD toward this polyphenolic metabolite.https://www.mdpi.com/2306-5710/6/3/50antioxidantsextractionhydroxypropyl β-cyclodextrinorange peelspolyphenols |
| spellingShingle | Achillia Lakka Stavros Lalas Dimitris P. Makris Hydroxypropyl-β-Cyclodextrin as a Green Co-Solvent in the Aqueous Extraction of Polyphenols from Waste Orange Peels Beverages antioxidants extraction hydroxypropyl β-cyclodextrin orange peels polyphenols |
| title | Hydroxypropyl-β-Cyclodextrin as a Green Co-Solvent in the Aqueous Extraction of Polyphenols from Waste Orange Peels |
| title_full | Hydroxypropyl-β-Cyclodextrin as a Green Co-Solvent in the Aqueous Extraction of Polyphenols from Waste Orange Peels |
| title_fullStr | Hydroxypropyl-β-Cyclodextrin as a Green Co-Solvent in the Aqueous Extraction of Polyphenols from Waste Orange Peels |
| title_full_unstemmed | Hydroxypropyl-β-Cyclodextrin as a Green Co-Solvent in the Aqueous Extraction of Polyphenols from Waste Orange Peels |
| title_short | Hydroxypropyl-β-Cyclodextrin as a Green Co-Solvent in the Aqueous Extraction of Polyphenols from Waste Orange Peels |
| title_sort | hydroxypropyl β cyclodextrin as a green co solvent in the aqueous extraction of polyphenols from waste orange peels |
| topic | antioxidants extraction hydroxypropyl β-cyclodextrin orange peels polyphenols |
| url | https://www.mdpi.com/2306-5710/6/3/50 |
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