Effect of a 16-Session Qigong Program in Non-Hodgkin Lymphoma Survivors: A Randomized Clinical Trial
Background: The treatment associated with non-Hodgkin lymphoma patients may cause adverse effects on their physical and psychological condition. The aim of this study is to detect the response to an eight-week, 16-session, 60-min presential Qigong program in anxiety, depression and vagal nerve activ...
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MDPI AG
2022-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/12/3421 |
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| author | Keyla Vargas-Román Emilia I. De la Fuente-Solana Jonathan Cortés-Martín Juan Carlos Sánchez-García Christian J. González-Vargas Lourdes Díaz-Rodríguez |
| author_facet | Keyla Vargas-Román Emilia I. De la Fuente-Solana Jonathan Cortés-Martín Juan Carlos Sánchez-García Christian J. González-Vargas Lourdes Díaz-Rodríguez |
| author_sort | Keyla Vargas-Román |
| collection | DOAJ |
| description | Background: The treatment associated with non-Hodgkin lymphoma patients may cause adverse effects on their physical and psychological condition. The aim of this study is to detect the response to an eight-week, 16-session, 60-min presential Qigong program in anxiety, depression and vagal nerve activity alongside a control group. Methods: A randomized controlled clinical trial was managed. Randomization was carried out by generating a numerical sequence of three cycles through the software EPIDAT 4.1. Numbers were placed in sealed opaque envelopes for assignment to the different groups. Results: Anxiety levels were substantially decreased in the experimental group, with a large effect size (F = 30.38, <i>p</i> < 0.00). Depression levels had an improvement in the experimental group in contrast to the control group, reaching statistical significance (F = 19.19, <i>p</i> < 0.00). Heart Rate Variability unveiled significant results in terms of between-group differences, with a large effect size in the HRV Index (F = 15.80, <i>p</i> < 0.00), SDNN (F = 8.82, <i>p</i> < 0.00), and RMSSD (F = 6.72, <i>p</i> < 0.01) in the time domain, and a medium effect size in the HF (F = 9.78, <i>p</i> < 0.003), LF (F = 9.78, <i>p</i> < 0.00), and LF/HF Ratio (F = 18.44, <i>p</i> < 0.00) in the frequency domain, which were all bettered in the experimental group, after the Qigong program. Conclusions: Qigong therapy can be an effective therapeutic activity in consonance with traditional medicine to improve psychological health and autonomic nervous system balance in non-Hodgkin lymphoma survivors. |
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| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T23:27:42Z |
| publishDate | 2022-06-01 |
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| spelling | doaj.art-cd4b30133ddf4d4885b278f119d0fdf52023-11-23T17:15:42ZengMDPI AGJournal of Clinical Medicine2077-03832022-06-011112342110.3390/jcm11123421Effect of a 16-Session Qigong Program in Non-Hodgkin Lymphoma Survivors: A Randomized Clinical TrialKeyla Vargas-Román0Emilia I. De la Fuente-Solana1Jonathan Cortés-Martín2Juan Carlos Sánchez-García3Christian J. González-Vargas4Lourdes Díaz-Rodríguez5Research Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainMethodology of Behavioral Sciences Department, Faculty of Psychology, University of Granada, 18071 Granada, SpainResearch Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainResearch Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainFulton Schools of Engineering Department, Faculty of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ 85281, USAResearch Group CTS1068, Andalusia Research Plan, Junta de Andalucía, 18014 Granada, SpainBackground: The treatment associated with non-Hodgkin lymphoma patients may cause adverse effects on their physical and psychological condition. The aim of this study is to detect the response to an eight-week, 16-session, 60-min presential Qigong program in anxiety, depression and vagal nerve activity alongside a control group. Methods: A randomized controlled clinical trial was managed. Randomization was carried out by generating a numerical sequence of three cycles through the software EPIDAT 4.1. Numbers were placed in sealed opaque envelopes for assignment to the different groups. Results: Anxiety levels were substantially decreased in the experimental group, with a large effect size (F = 30.38, <i>p</i> < 0.00). Depression levels had an improvement in the experimental group in contrast to the control group, reaching statistical significance (F = 19.19, <i>p</i> < 0.00). Heart Rate Variability unveiled significant results in terms of between-group differences, with a large effect size in the HRV Index (F = 15.80, <i>p</i> < 0.00), SDNN (F = 8.82, <i>p</i> < 0.00), and RMSSD (F = 6.72, <i>p</i> < 0.01) in the time domain, and a medium effect size in the HF (F = 9.78, <i>p</i> < 0.003), LF (F = 9.78, <i>p</i> < 0.00), and LF/HF Ratio (F = 18.44, <i>p</i> < 0.00) in the frequency domain, which were all bettered in the experimental group, after the Qigong program. Conclusions: Qigong therapy can be an effective therapeutic activity in consonance with traditional medicine to improve psychological health and autonomic nervous system balance in non-Hodgkin lymphoma survivors.https://www.mdpi.com/2077-0383/11/12/3421lymphoma cancerHRVautonomic nervous systemnon-Hodgkin lymphomaanxietydepression |
| spellingShingle | Keyla Vargas-Román Emilia I. De la Fuente-Solana Jonathan Cortés-Martín Juan Carlos Sánchez-García Christian J. González-Vargas Lourdes Díaz-Rodríguez Effect of a 16-Session Qigong Program in Non-Hodgkin Lymphoma Survivors: A Randomized Clinical Trial Journal of Clinical Medicine lymphoma cancer HRV autonomic nervous system non-Hodgkin lymphoma anxiety depression |
| title | Effect of a 16-Session Qigong Program in Non-Hodgkin Lymphoma Survivors: A Randomized Clinical Trial |
| title_full | Effect of a 16-Session Qigong Program in Non-Hodgkin Lymphoma Survivors: A Randomized Clinical Trial |
| title_fullStr | Effect of a 16-Session Qigong Program in Non-Hodgkin Lymphoma Survivors: A Randomized Clinical Trial |
| title_full_unstemmed | Effect of a 16-Session Qigong Program in Non-Hodgkin Lymphoma Survivors: A Randomized Clinical Trial |
| title_short | Effect of a 16-Session Qigong Program in Non-Hodgkin Lymphoma Survivors: A Randomized Clinical Trial |
| title_sort | effect of a 16 session qigong program in non hodgkin lymphoma survivors a randomized clinical trial |
| topic | lymphoma cancer HRV autonomic nervous system non-Hodgkin lymphoma anxiety depression |
| url | https://www.mdpi.com/2077-0383/11/12/3421 |
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