QingXiaoWuWei decoction alleviates methicillin-resistant Staphylococcus aureus-induced pneumonia in mice by regulating metabolic remodeling and macrophage gene expression network via the microbiota-short-chain fatty acids axis

QingXiaoWuWei decoction alleviates methicillin-resistant Staphylococcus aureus-induced pneumonia in mice by regulating metabolic remodeling and macrophage gene expression network via the microbiota-short-chain fatty acids axis

ABSTRACT QingXiaoWuWei decoction (QXWWD) exerts a prominent therapeutic effect on the methicillin-resistant Staphylococcus aureus (MRSA)-induced pneumonia model in mice; however, its pharmacological mechanisms remain unclear. This study aimed to investigate the underlying pharmacological mechanisms...

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Bibliographic Details
Main Authors:	Jun Li, Qian Zhang, Xue Li, Jing Liu, Fang Wang, Wei Zhang, Xingyue Liu, Tiewei Li, Shiqi Wang, Yuqi Wang, Xinyu Zhang, Yukun Meng, Yuheng Ma, Huanyun Wang
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-12-01
Series:	Microbiology Spectrum
Subjects:	QingXiaoWuWei decoction MRSA-induced pneumonia microbiota-SCFAs axis multi-omics approaches metabolic remodeling macrophage gene expression network
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00344-23

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